Secretin (porcine) Hydrochloride

Molecular Formula C₁₃₀H₂₂₀N₄₄O₄₁

Relative Molecular Mass 3055.45 g/mol

CAS-Number 17034-35-4 (net)

Long-term Storage -20 ± 5°C

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Secretin (porcine) Hydrochloride

H-3780-GMP, 4041451

Bachem Regulatory Documentation

DMF

Sequence

H-His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Arg-Asp-Ser-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH₂ hydrochloride salt

Fields of Application

Diagnosis of pancreatic exocrine dysfunction
Diagnosis of gastrinoma
Aid in endoscopic retrograde cholangiopancreatography

Active Substance

Secretin is produced by the S cells of the duodenum. The peptide hormone regulates the pH in the duodenal system, as secretin stimulates the secretion of bicarbonate by the pancreas and inhibits the gastric acid and gastrin production in the stomach. Additionally, secretin potentiates the release of digestive enzymes from the pancreas triggered by cholecystokinin.
Secretin also plays a role in the regulation of body water homeostasis.

Also available

Related Research Grade Peptides

H-3780	Secretin (porcine)
H-3022	Secretin (human)
H-5498	Secretin (rat)
H-4940	Secretin (5-27) (porcine)

Related Radiolabeled Peptides

H-5236	([¹²⁵I]-Tyr)-Secretin (porcine) CE-marked Liquid
H-6968	([¹²⁵I]-Tyr)-Secretin (porcine) CE-marked Lyophilized

Related Immunology Products

S-2190	Secretin (porcine) - RIA Kit, Host: Rabbit CE-marked
S-1230	Secretin (porcine) - EIA Kit, Host: Rabbit High Sensitivity CE-marked
S-4031	Secretin (porcine) - Immunohistochemistry Staining Kit , Host: Rabbit
S-3125	Secretin (porcine) - Immunofluorescence Kit, Host: Rabbit
T-4541	Secretin (porcine) - Diluted Antiserum for RIA , Host: Rabbit
T-4542	Secretin (porcine) - Purified Antiserum - IgG, Host: Rabbit
T-4543	Secretin (porcine) - Undiluted Antiserum for Immunohistochemistry, Host: Rabbit