Bradykinin Acetate 50 µg/vial (Clinalfa basic)

U-1080

A considerable number of publications on Clinalfa products used in clinical trials are available. The most important publications are listed below. For a comprehensive list please contact us.

 

All information is compiled to the best of our knowledge. We cannot be made liable for any possible errors or misprints.

Clinalfa

Literature references citing the Clinalfa basic product

2011

Ozkor, M. A., Murrow, J. R., Rahman, A. M., Kavtaradze, N., Lin, J., Manatunga, A. and Quyyumi, A. A.
Endothelium-derived hyperpolarizing factor determines resting and stimulated forearm vasodilator tone in health and in disease.
Circulation 123, 2244-2253 (2011)
Abstract

 

2010

Pretorius, M. and Brown, N. J.
Endogenous nitric oxide contributes to bradykinin-stimulated glucose uptake but attenuates vascular tissue-type plasminogen activator release.
J. Pharmacol. Exp. Ther. 332, 291-297 (2010)
Abstract

 

2009

Gunaruwan, P., Maher, A., Williams, L., Sharman, J., Schmitt, M., Campbell, R. and Frenneaux, M.
Effects of bradykinin on venous capacitance in health and treated chronic heart failure.
Clin. Sci. (Lond) 116, 443-450 (2009)
Abstract

 

 2008

Dias, M. P., Newton, D. J., McLeod, G. A., Khan, F. and Belch, J. J.
The inhibitory effects of local anaesthetics on the vascular flare responses to bradykinin and substance P in human skin.
Anaesthesia 63, 151-155 (2008)
Abstract

Lang, N. N., Gudmundsdottir, I. J., Boon, N. A., Ludlam, C. A., Fox, K. A. and Newby, D. E.
Marked impairment of protease-activated receptor type 1-mediated vasodilation and fibrinolysis in cigarette smokers: smoking, thrombin, and vascular responses in vivo.
J. Am. Coll. Cardiol. 52, 33-39 (2008)
Abstract

Van Guilder, G. P., Stauffer, B. L., Greiner, J. J. and Desouza, C. A.
Impaired endothelium-dependent vasodilation in overweight and obese adult humans is not limited to muscarinic receptor agonists.
Am. J. Physiol. Heart Circ. Physiol. 294, H1685-1692 (2008)
Abstract

 

2007

Mills, N. L., Tornqvist, H., Gonzalez, M. C., Vink, E., Robinson, S. D., Soderberg, S., Boon, N. A., Donaldson, K., Sandstrom, T., Blomberg, A. and Newby, D. E.
Ischemic and thrombotic effects of dilute diesel-exhaust inhalation in men with coronary heart disease.
N. Engl. J. Med. 357, 1075-1082 (2007)
Abstract

 

2006

Battaglia, S., Angus, P. and Chin-Dusting, J. P.
Role of the endothelium on vasoactive agents in patients with liver cirrhosis.
J. Gastroenterol. Hepatol. 21, 1189-1193 (2006)

Helmy, A., Ferguson, J. W., Hayes, P. C., Newby, D. E. and Webb, D. J.
Bradykinin does not contribute to peripheral vascular tone in patients with cirrhosis and ascites.
J. Cardiovasc. Pharmacol. 47, 556-560 (2006)
Abstract

Murphey, L. J., Malave, H. A., Petro, J., Biaggioni, I., Byrne, D. W., Vaughan, D. E., Luther, J. M., Pretorius, M. and Brown, N. J.
Bradykinin and its metabolite bradykinin 1-5 inhibit thrombin-induced platelet aggregation in humans.
J. Pharmacol. Exp. Ther. 318, 1287-1292 (2006)
Abstract

 

2005

Kamper, A. M., de Craen, A. J., Westendorp, R. G. and Blauw, G. J.
Endothelium-dependent NO-mediated vasodilation in humans is attenuated by peripheral alpa1-adrenoceptor activation.
Vasc. Health Risk Manag. 1, 251-256 (2005)
Abstract

Schrage, W. G., Dietz, N. M., Eisenach, J. H. and Joyner, M. J.
Agonist-dependent variablity of contributions of nitric oxide and prostaglandins in human skeletal muscle.
J. Appl. Physiol. 98, 1251-1257 (2005)
Abstract

 

2004

Clapp, B. R., Hingorani, A. D., Kharbanda, R. K., Mohamed-Ali, V., Stephens, J. W., Vallance, P. and MacAllister, R. J.
Inflammation-induced endothelial dysfunction involves reduced nitric oxide bioavailability and increased oxidant stress.
Cardiovasc. Res. 64, 172-178 (2004)
Abstract

Cruden, N. L., Fox, K. A., Ludlam, C. A., Johnston, N. R. and Newby, D. E.
Neutral endopeptidase inhibition augments vascular actions of bradykinin in patients treated with angiotensin-converting enzyme inhibition.
Hypertension 44, 913-918 (2004)
Abstract

Cruden, N. L., Witherow, F. N., Webb, D. J., Fox, K. A. and Newby, D. E.
Bradykinin contributes to the systemic hemodynamic effects of chronic angiotensin-converting enzyme inhibition in patients with heart failure.
Arterioscler. Thromb. Vasc. Biol. 24, 1043-1048 (2004)
Abstract

 

2003

Chan, N. N., Fuller, J. H., Rubens, M. and Colhoun, H. M.
Von Willebrand factor in type 1 diabetes: its production and coronary artery calcification.
Med. Sci. Monit. 9, CR297-303 (2003)
Abstract

Chia, S., Ludlam, C. A., Fox, K. A. and Newby, D. E.
Acute systemic inflammation enhances endothelium-dependent tissue plasminogen activator release in men.
J. Am. Coll. Cardiol. 41, 333-339 (2003)
Abstract

Grahame-Clarke, C., Chan, N. N., Andrew, D., Ridgway, G. L., Betteridge, D. J., Emery, V., Colhoun, H. M. and Vallance, P.
Human cytomegalovirus seropositivity is associated with impaired vascular function.
Circulation 108, 678-683 (2003)
Abstract

Guthikonda, S., Sinkey, C., Barenz, T. and Haynes, W. G.
Xanthine oxidase inhibition reverses endothelial dysfunction in heavy smokers.
Circulation 107, 416-421 (2003)
Abstract

Hoetzer, G. L., Stauffer, B. L., Greiner, J. J., Casas, Y., Smith, D. T. and DeSouza, C. A.
Influence of oral contraceptive use on endothelial t-PA release in healthy premenopausal women.
Am. J. Physiol. Endocrinol. Metab. 284, E90-95 (2003)
Abstract

Kemme, M. J., Burggraaf, J., Schoemaker, R. C., Cohen, A. F., Kluft, C., Chia, S., Webb, D. J. and Newby, D. E.
Local tissue factor pathway inhibitor release in the human forearm.
Thromb. Haemost. 89, 438-445 (2003)
Abstract

Lauer, T., Kleinbongard, P., Preik, M., Rauch, B. H., Deussen, A., Feelisch, M., Strauer, B. E. and Kelm, M.
Direct biochemical evidence for eNOS stimulation by bradykinin in the human forearm vasculature.
Basic. Res. Cardiol. 98, 84-89 (2003)
Abstract

Mork, H., Ashina, M., Bendtsen, L., Olesen, J. and Jensen, R.
Experimental muscle pain and tenderness following infusion of endogenous substances in humans.
Eur. J. Pain 7, 145-153 (2003)
Abstract

Passauer, J., Bussemaker, E., Lassig, G., Pistrosch, F., Fauler, J., Gross, P. and Fleming, I.
Baseline blood flow and bradykinin-induced vasodilator responses in the human forearm are insensitive to the cytochrome P450 2C9 (CYP2C9) inhibitor sulphaphenazole.
Clin. Sci. (Lond) 105, 513-518 (2003)
Abstract

Pretorius, M., Rosenbaum, D., Vaughan, D. E. and Brown, N. J.
Angiotensin-converting enzyme inhibition increases human vascular tissue-type plasminogen activator release through endogenous bradykinin.
Circulation 107, 579-585 (2003)
Abstract

Schram, M. T., Stam, F., de Jongh, R. T., de Vries, G., van Dijk, R. A., Serne, E. H., Lampe, D., Nanayakkara, P. W., Tushuizen, M. E., Scheffer, P. G., Schalkwijk, C. G., Kamper, A. M. and Stehouwer, C. D.
The effect of calcium dobesilate on vascular endothelial function, blood pressure, and markers of oxidation in obese male smokers: a placebo-controlled randomised clinical trial.
Atherosclerosis 170, 59-72 (2003)
Abstract

Smith, D. T., Hoetzer, G. L., Greiner, J. J., Stauffer, B. L. and DeSouza, C. A.
Endothelial release of tissue-type plasminogen activator in the human forearm: role of nitric oxide.
J. Cardiovasc. Pharmacol. 42, 311-314 (2003)
Abstract

Taddei, S., Virdis, A., Ghiadoni, L., Versari, D., Salvetti, G., Magagna, A. and Salvetti, A.
Calcium antagonist treatment by lercanidipine prevents hyperpolarization in essential hypertension.
Hypertension 41, 950-955 (2003)
Abstract

Vigili de Kreutzenberg, S., Kiwanuka, E., Tiengo, A. and Avogaro, A.
Visceral obesity is characterized by impaired nitric oxide-independent vasodilation.
Eur. Heart J. 24, 1210-1215 (2003)
Abstract

 

2002

Chan, N. N., Vallance, P., Colhoun, H. M., MacAllister, R. J., Hingorani, A. D. and Conway, G. S.
The effects of hormone replacement therapy on endothelial function in women with Turner's syndrome.
Clin. Endocrinol. (Oxf) 56, 615-620 (2002)
Abstract

Davie, A. P. and McMurray, J. J.
Effect of aspirin on vasodilation to bradykinin and substance P in patients with heart failure treated with ACE inhibitor.
Br. J. Clin. Pharmacol. 53, 37-42 (2002)
Abstract

DeSouza, C. A., Clevenger, C. M., Greiner, J. J., Smith, D. T., Hoetzer, G. L., Shapiro, L. F. and Stauffer, B. L.
Evidence for agonist-specific endothelial vasodilator dysfunction with ageing in healthy humans.
J. Physiol. 542, 255-262 (2002)
Abstract

Kharbanda, R. K., Walton, B., Allen, M., Klein, N., Hingorani, A. D., MacAllister, R. J. and Vallance, P.
Prevention of inflammation-induced endothelial dysfunction: a novel vasculo-protective action of aspirin.
Circulation 105, 2600-2604 (2002)
Abstract

Pretorius, M., Rosenbaum, D. A., Lefebvre, J., Vaughan, D. E. and Brown, N. J.
Smoking impairs bradykinin-stimulated t-PA release.
Hypertension 39, 767-771 (2002)
Abstract

Singh, N., Graves, J., Taylor, P. D., MacAllister, R. J. and Singer, D. R.
Effects of a 'healthy' diet and of acute and long-term vitamin C on vascular function in healthy older subjects.
Cardiovasc. Res. 56, 118-125 (2002)
Abstract

Witherow, F. N., Dawson, P., Ludlam, C. A., Fox, K. A. and Newby, D. E.
Marked bradykinin-induced tissue plasminogen activator release in patients with heart failure maintained on long-term angiotensin-converting enzyme inhibitor therapy.
J. Am. Coll. Cardiol. 40, 961-966 (2002)
Abstract

 

2001

Ceballos, C., Ribes, C., Amado, J. A., de Mier, I., de Rozas, L. S. and Berrazueta, J. R.
Venous endothelial function in postmenopausal women after six months of tibolone therapy.
Maturitas 39, 63-70 (2001)
Abstract

Chan, N. N., Colhoun, H. M. and Vallance, P.
Cardiovascular risk factors as determinants of endothelium-dependent and endothelium-independent vascular reactivity in the general population.
J. Am. Coll. Cardiol. 38, 1814-1820 (2001)
Abstract

Chan, N. N., MacAllister, R. J., Colhoun, H. M., Vallance, P. and Hingorani, A. D.
Changes in endothelium-dependent vasodilatation and alpha-adrenergic responses in resistance vessels during the menstrual cycle in healthy women.
J. Clin. Endocrinol. Metab. 86, 2499-2504 (2001)
Abstract

Clive, S., Webb, D. J., MacLellan, A., Young, A., Byrne, B., Robson, L., Smyth, J. F. and Jodrell, D. I.
Forearm blood flow and local responses to peptide vasodilators: a novel pharmacodynamic measure in the phase I trial of antagonist G, a neuropeptide growth factor antagonist.
Clin. Cancer. Res. 7, 3071-3078 (2001)
Abstract

Labinjoh, C., Newby, D. E., Pellegrini, M. P., Johnston, N. R., Boon, N. A. and Webb, D. J.
Potentiation of bradykinin-induced tissue plasminogen activator release by angiotensin-converting enzyme inhibition.
J. Am. Coll. Cardiol. 38, 1402-1408 (2001)
Abstract

Raghuveer, G., Sinkey, C. A., Chenard, C., Stumbo, P. and Haynes, W. G.
Effect of vitamin E on resistance vessel endothelial dysfunction induced by methionine.
Am. J. Cardiol. 88, 285-290 (2001)
Abstract

Taddei, S., Virdis, A., Ghiadoni, L., Magagna, A., Pasini, A. F., Garbin, U., Cominacini, L. and Salvetti, A.
Effect of calcium antagonist or beta blockade treatment on nitric oxide-dependent vasodilation and oxidative stress in essential hypertensive patients.
J. Hypertens. 19, 1379-1386 (2001)
Abstract

Witherow, F. N., Helmy, A., Webb, D. J., Fox, K. A. and Newby, D. E.
Bradykinin contributes to the vasodilator effects of chronic angiotensin-converting enzyme inhibition in patients with heart failure.
Circulation 104, 2177-2181 (2001)
Abstract

 

2000

Aptecar, E., Teiger, E., Dupouy, P., Benvenuti, C., Kern, M. J., Woscoboinik, J., Sediame, S., Pernes, J. M., Castaigne, A., Loisance, D. and Dubois-Rande, J. L.
Effects of bradykinin on coronary blood flow and vasomotion in transplant patients.
J. Am. Coll. Cardiol. 35, 1607-1615 (2000)
Abstract

Babenko, V., Svensson, P., Graven-Nielsen, T., Drewes, A. M., Jensen, T. S. and Arendt-Nielsen, L.
Duration and distribution of experimental muscle hyperalgesia in humans following combined infusions of serotonin and bradykinin.
Brain Res. 853, 275-281 (2000)
Abstract

Ceballos, C., Ribes, C., Amado, J. A., Perez, J., Garcia Unzueta, M. T. and de Berrazueta, J. R.
Venous endothelial function in postmenopausal women who are receiving long-term estrogen and progestagen therapy.
Fertil. Steril. 74, 268-273 (2000)
Abstract

Frossard, M., Joukhadar, C., Steffen, G., Schmid, R., Eichler, H. G. and Muller, M.
Paracrine effects of angiotensin-converting-enzyme- and angiotensin-II-receptor- inhibition on transcapillary glucose transport in humans.
Life Sci. 66, PL147-154 (2000)
Abstract

Hingorani, A. D., Cross, J., Kharbanda, R. K., Mullen, M. J., Bhagat, K., Taylor, M., Donald, A. E., Palacios, M., Griffin, G. E., Deanfield, J. E., MacAllister, R. J. and Vallance, P.
Acute systemic inflammation impairs endothelium-dependent dilatation in humans.
Circulation 102, 994-999 (2000)
Abstract

Honing, M. L., Smits, P., Morrison, P. J. and Rabelink, T. J.
Bradykinin-induced vasodilation of human forearm resistance vessels is primarily mediated by endothelium-dependent hyperpolarization.
Hypertension 35, 1314-1318 (2000)
Abstract

Kimura, M., Watanabe, H., Takahashi, R., Kosuge, K., Umemura, K., Hayashi, H., Ohashi, K. and Ohno, R.
Inhibitory effect of insulin on bradykinin-induced venodilation.
J. Hypertens. 18, 287-292 (2000)
Abstract

Labinjoh, C., Newby, D. E., Dawson, P., Johnston, N. R., Ludlam, C. A., Boon, N. A. and Webb, D. J.
Fibrinolytic actions of intra-arterial angiotensin II and bradykinin in vivo in man.
Cardiovasc. Res. 47, 707-714 (2000)
Abstract

Sabha, M., Tanus-Santos, J. E., Toledo, J. C., Cittadino, M., Rocha, J. C. and Moreno, H., Jr.
Transdermal nicotine mimics the smoking-induced endothelial dysfunction.
Clin. Pharmacol. Ther. 68, 167-174 (2000)
Abstract

van Dijk, M. A., Kroon, I., Kamper, A. M., Boomsma, F., Danser, A. H. and Chang, P. C.
The angiotensin-converting enzyme gene polymorphism and responses to angiotensins and bradykinin in the human forearm.
J. Cardiovasc. Pharmacol. 35, 484-490 (2000)
Abstract

 

1999

Babenko, V., Graven-Nielsen, T., Svensson, P., Drewes, A. M., Jensen, T. S. and Arendt-Nielsen, L.
Experimental human muscle pain and muscular hyperalgesia induced by combinations of serotonin and bradykinin.
Pain 82, 1-8 (1999)
Abstract

Babenko, V. V., Graven-Nielsen, T., Svensson, P., Drewes, A. M., Jensen, T. S. and Arendt-Nielsen, L.
Experimental human muscle pain induced by intramuscular injections of bradykinin, serotonin, and substance P.
Eur. J. Pain 3, 93-102 (1999)
Abstract

Barba, G., Mullen, M. J., Donald, A. and MacAllister, R. J.
Determinants of the response of human blood vessels to nitric oxide donors in vivo.
J. Pharmacol. Exp. Ther. 289, 1662-1668 (1999)
Abstract

Clough, G. F.
Role of nitric oxide in the regulation of microvascular perfusion in human skin in vivo.
J. Physiol. 516 ( Pt 2), 549-557 (1999)
Abstract

Davie, A. P., Dargie, H. J. and McMurray, J. J.
Role of bradykinin in the vasodilator effects of losartan and enalapril in patients with heart failure.
Circulation 100, 268-273 (1999)
Abstract

Davie, A. P. and McMurray, J. J.
Effect of angiotensin-(1-7) and bradykinin in patients with heart failure treated with an ACE inhibitor.
Hypertension 34, 457-460 (1999)
Abstract

Gaspardone, A., Crea, F., Tomai, F., Versaci, F., Pellegrino, A., Chiariello, L. and Gioffre, P. A.
Effect of acetylsalicylate on cardiac and muscular pain induced by intracoronary and intra-arterial infusion of bradykinin in humans.
J. Am. Coll. Cardiol. 34, 216-222 (1999)
Abstract

Taddei, S., Ghiadoni, L., Virdis, A., Buralli, S. and Salvetti, A.
Vasodilation to bradykinin is mediated by an ouabain-sensitive pathway as a compensatory mechanism for impaired nitric oxide availability in essential hypertensive patients.
Circulation 100, 1400-1405 (1999)
Abstract

Wilson, D. G., Bellamy, M. F., Ramsey, M. W., Goodfellow, J., Brownlee, M., Davies, S., Wilson, J. F., Lewis, M. J. and Stuart, A. G.
Endothelial function in Marfan syndrome: selective impairment of flow-mediated vasodilation.
Circulation 99, 909-915 (1999)
Abstract

 

1998

Taddei, S., Virdis, A., Ghiadoni, L., Mattei, P. and Salvetti, A.
Effects of angiotensin converting enzyme inhibition on endothelium-dependent vasodilatation in essential hypertensive patients.
J. Hypertens. 16, 447-456 (1998)
Abstract

Wenzel, R. R., Zbinden, S., Noll, G., Meier, B. and Luscher, T. F.
Endothelin-1 induces vasodilation in human skin by nociceptor fibres and release of nitric oxide.
Br. J. Clin. Pharmacol. 45, 441-446 (1998)
Abstract

 

1997

Haefeli, W. E., Linder, L. and Luscher, T. F.
Quinaprilat induces arterial vasodilation mediated by nitric oxide in humans.
Hypertension 30, 912-917 (1997)
Abstract

Kuga, T., Mohri, M., Egashira, K., Hirakawa, Y., Tagawa, T., Shimokawa, H. and Takeshita, A.
Bradykinin-induced vasodilation of human coronary arteries in vivo: role of nitric oxide and angiotensin-converting enzyme.
J. Am. Coll. Cardiol. 30, 108-112 (1997)
Abstract

Newby, D. E., Masumori, S., Johnston, N. R., Boon, N. A. and Webb, D. J.
Endogenous angiotensin II contributes to basal peripheral vascular tone in sodium deplete but not sodium replete man.
Cardiovasc. Res. 36, 268-275 (1997)
Abstract

Taddei, S., Virdis, A., Ghiadoni, L., Uleri, S., Magagna, A. and Salvetti, A.
Lacidipine restores endothelium-dependent vasodilation in essential hypertensive patients.
Hypertension 30, 1606-1612 (1997)
Abstract

 

1996

Bhagat, K., Moss, R., Collier, J. and Vallance, P.
Endothelial "stunning" following a brief exposure to endotoxin: a mechanism to link infection and infarction?
Cardiovasc. Res. 32, 822-829 (1996)
Abstract

Chadwick, I. G., Kraskiewicz, M., Yeo, W. W., Higgins, K. S., Jackson, P. R. and Ramsay, L. E.
No relation between angiotensin-converting enzyme gene polymorphism and dermal response to bradykinin in healthy subjects.
Clin. Sci. (Lond) 91, 617-620 (1996)
Abstract

Dear, J. W., Ghali, S. and Foreman, J. C.
Attenuation of human nasal airway responses to bradykinin and histamine by inhibitors of nitric oxide synthase.
Br. J. Pharmacol. 118, 1177-1182 (1996)
Abstract

Strobel, W. M., Luscher, T. F., Simper, D., Linder, L. and Haefeli, W. E.
Substance P in human hand veins in vivo: tolerance, efficacy, potency, and mechanism of venodilator action.
Clin. Pharmacol. Ther. 60, 435-443 (1996)
Abstract

 

1995

Kindgen-Milles, D.
Effects of prostaglandin E2 on the intensity of bradykinin-evoked pain from skin and veins of humans.
Eur. J. Pharmacol. 294, 491-496 (1995)
Abstract

 

1994

Cockcroft, J. R., Chowienczyk, P. J., Brett, S. E. and Ritter, J. M.
Effect of NG-monomethyl-L-arginine on kinin-induced vasodilation in the human forearm.
Br. J. Clin. Pharmacol. 38, 307-310 (1994)
Abstract

Kindgen-Milles, D., Klement, W. and Arndt, J. O.
The nociceptive systems of skin, paravascular tissue and hand veins of humans and their sensitivity to bradykinin.
Neurosci. Lett. 181, 39-42 (1994)
Abstract

 

Literature references citing the active pharmaceutical ingredient (API)

 2004

Matsumoto, T., Takashima, H., Ohira, N., Tarutani, Y., Yasuda, Y., Yamane, T., Matsuo, S. and Horie, M.
Plasma level of oxidized low-density lipoprotein is an independent determinant of coronary macrovasomotor and microvasomotor responses induced by bradykinin.
J. Am. Coll. Cardiol. 44, 451-457 (2004)
Abstract

Wei, M., Wang, X., Kuukasjarvi, P., Laurikka, J., Rinne, T., Honkonen, E. L. and Tarkka, M.
Bradykinin preconditioning in coronary artery bypass grafting.
Ann. Thorac. Surg. 78, 492-497 (2004)
Abstract

 

2003

Brown, H., Moppett, I. K. and Mahajan, R. P.
Transient hyperaemic response to assess vascular reactivity of skin: effect of locally iontophoresed acetylcholine, bradykinin, epinephrine and phenylephrine.
Br. J. Anaesth. 90, 446-451 (2003)
Abstract

de Kreutzenberg, S. V., Puato, M., Kiwanuka, E., Del Prato, S., Pauletto, P., Pasini, L., Tiengo, A. and Avogaro, A.
Elevated non-esterified fatty acids impair nitric oxide independent vasodilation, in humans: evidence for a role of inwardly rectifying potassium channels.
Atherosclerosis 169, 147-153 (2003)
Abstract

Inokuchi, K., Hirooka, Y., Shimokawa, H., Sakai, K., Kishi, T., Ito, K., Kimura, Y. and Takeshita, A.
Role of endothelium-derived hyperpolarizing factor in human forearm circulation.
Hypertension 42, 919-924 (2003)
Abstract

Matsumoto, T., Minai, K., Horie, H., Ohira, N., Takashima, H., Tarutani, Y., Yasuda, Y., Ozawa, T., Matsuo, S., Kinoshita, M. and Horie, M.
Angiotensin-converting enzyme inhibition but not angiotensin II type 1 receptor antagonism augments coronary release of tissue plasminogen activator in hypertensive patients.
J. Am. Coll. Cardiol. 41, 1373-1379 (2003)
Abstract

Mork, H., Ashina, M., Bendtsen, L., Olesen, J. and Jensen, R.
Induction of prolonged tenderness in patients with tension-type headache by means of a new experimental model of myofascial pain.
Eur. J. Neurol. 10, 249-256 (2003)
Abstract

Playford, D. A., Watts, G. F., Croft, K. D. and Burke, V.
Combined effect of coenzyme Q10 and fenofibrate on forearm microcirculatory function in type 2 diabetes.
Atherosclerosis 168, 169-179 (2003)
Abstract

 

2002

Hirooka, K., Shiraga, F. and Hasegawa, E.
Bradykinin sensitivity in primary open-angle glaucoma and normal-tension glaucoma patients.
Am. J. Ophthalmol. 134, 922-924 (2002)
Abstract

Rosenbaum, D. A., Pretorius, M., Gainer, J. V., Byrne, D., Murphey, L. J., Painter, C. A., Vaughan, D. E. and Brown, N. J.
Ethnicity affects vasodilation, but not endothelial tissue plasminogen activator release, in response to bradykinin.
Arterioscler. Thromb. Vasc. Biol. 22, 1023-1028 (2002)
Abstract

Yokohama, H., Matsumoto, T., Horie, H., Minai, K. and Kinoshita, M.
Coronary endothelium-dependent and independent vasomotor responses in patients with hypertrophic cardiomyopathy.
Circ. J. 66, 30-34 (2002)
Abstract

 

2001

Arcaro, G., Solini, A., Monauni, T., Cretti, A., Brunato, B., Lechi, A., Fellin, R., Caputo, M., Cocco, C., Bonora, E., Muggeo, M. and Bonadonna, R. C.
ACE genotype and endothelium-dependent vasodilation of conduit arteries and forearm microcirculation in humans.
Arterioscler. Thromb. Vasc. Biol. 21, 1313-1319 (2001)
Abstract

Gainer, J. V., Stein, C. M., Neal, T., Vaughan, D. E. and Brown, N. J.
Interactive Effect of Ethnicity and ACE Insertion/Deletion Polymorphism on Vascular Reactivity.
Hypertension 37, 46-51 (2001)
Abstract

Horie, H., Matsumoto, T., Takahashi, M., Nakazawa, Y., Yokohama, H., Minai, K. and Kinoshita, M.
Angiographically documented coronary steal phenomenon evoked by the intracoronary infusion of bradykinin.
Jpn. Circ. J. 65, 123-125 (2001)
Abstract

Lischetzki, G., Rukwied, R., Handwerker, H. O. and Schmelz, M.
Nociceptor activation and protein extravasation induced by inflammatory mediators in human skin.
Eur. J. Pain. 5, 49-57 (2001)
Abstract

Maguire, S. M., McAuley, D., McGurk, C., Nugent, A. G., Johnston, G. D. and Nicholls, D. P.
Bradykinin infusion in chronic cardiac failure and the effects of captopril.
Eur. J. Heart Fail. 3, 671-677 (2001)
Abstract

Matsumoto, T., Horie, H., Minai, K., Yokohama, H., Takashima, H., Ohira, N., Tsutui, T., Takahashi, M. and Kinoshita, M.
Coronary vasomotor responses to bradykinin and acetylcholine in patients with coronary spastic angina.
Jpn. Circ. J. 65, 1052-1056 (2001)
Abstract

Minai, K., Matsumoto, T., Horie, H., Ohira, N., Takashima, H., Yokohama, H. and Kinoshita, M.
Bradykinin stimulates the release of tissue plasminogen activator in human coronary circulation: effects of angiotensin-converting enzyme inhibitors.
J. Am. Coll. Cardiol. 37, 1565-1570 (2001)
Abstract

Newton, D. J., Khan, F. and Belch, J. J.
Assessment of microvascular endothelial function in human skin.
Clin. Sci. (Lond) 101, 567-572 (2001)
Abstract

Prasad, A., Mincemoyer, R. and Quyyumi, A. A.
Anti-ischemic effects of angiotensin- converting enzyme inhibition in hypertension.
J. Am. Coll. Cardiol. 38, 1116-1122 (2001)
Abstract

Ricciardolo, F. L., Timmers, M. C., Geppetti, P., van Schadewijk, A., Brahim, J. J., Sont, J. K., de Gouw, H. W., Hiemstra, P. S., van Krieken, J. H. and Sterk, P. J.
Allergen-induced impairment of bronchoprotective nitric oxide synthesis in asthma.
J. Allergy Clin. Immunol. 108, 198-204 (2001)
Abstract

Wilsdorf, T., Gainer, J. V., Murphey, L. J., Vaughan, D. E. and Brown, N. J.
Angiotensin-(1-7) does not affect vasodilator or TPA responses to bradykinin in human forearm.
Hypertension 37, 1136-1140 (2001)
Abstract

 

2000

Brown, N. J., Gainer, J. V., Murphey, L. J. and Vaughan, D. E.
Bradykinin stimulates tissue plasminogen activator release from human forearm vasculature through B(2) receptor-dependent, NO synthase-independent, and cyclooxygenase-independent pathway.
Circulation 102, 2190-2196 (2000)
Abstract

Chalon, S., Moreno, H., Jr., Benowitz, N. L., Hoffman, B. B. and Blaschke, T. F.
Nicotine impairs endothelium-dependent dilatation in human veins in vivo.
Clin. Pharmacol. Ther. 67, 391-397 (2000)
Abstract

Duchna, H. W., Guilleminault, C., Stoohs, R. A., Faul, J. L., Moreno, H., Hoffman, B. B. and Blaschke, T. F.
Vascular reactivity in obstructive sleep apnea syndrome.
Am. J. Respir. Crit. Care Med. 161, 187-191 (2000)
Abstract

Kim, K. S., Kumar, S., Simmons, W. H. and Brown, N. J.
Inhibition of aminopeptidase P potentiates wheal response to bradykinin in angiotensin-converting enzyme inhibitor-treated humans.
J. Pharmacol. Exp. Ther. 292, 295-298 (2000)
Abstract

Maniscalco, M., Sofia, M., Faraone, S. and Carratu, L.
The effect of platelet-activating factor (PAF) on nasal airway resistance in healthy subjects is not mediated by nitric oxide.
Allergy 55, 757-761 (2000)
Abstract

Murphey, L. J., Gainer, J. V., Vaughan, D. E. and Brown, N. J.
Angiotensin-converting enzyme insertion/deletion polymorphism modulates the human in vivo metabolism of bradykinin.
Circulation 102, 829-832 (2000)
Abstract

Murphey, L. J., Hachey, D. L., Oates, J. A., Morrow, J. D. and Brown, N. J.
Metabolism of bradykinin In vivo in humans: identification of BK1-5 as a stable plasma peptide metabolite.
J. Pharmacol. Exp. Ther. 294, 263-269 (2000)
Abstract

Prasad, A., Husain, S., Schenke, W., Mincemoyer, R., Epstein, N. and Quyyumi, A. A.
Contribution of bradykinin receptor dysfunction to abnormal coronary vasomotion in humans.
J. Am. Coll. Cardiol. 36, 1467-1473 (2000)
Abstract

 

1999

Benacerraf, S., Carville, C., Adnot, S., Montagne, O., Sediame, S., Belhassen, L. and Dubois-Rande, J. L.
Improvement of bradykinin endothelium-mediated vasodilation of forearm resistance circulation by quinaprilat in patients with coronary artery disease with or without left ventricular dysfunction.
J. Cardiovasc. Pharmacol. 34, 368-373 (1999)
Abstract

Berkenboom, G., Crasset, V., Unger, P., Vachiery, J. L. and LeClerc, J. L.
Absence of L-arginine effect on coronary hypersensitivity to serotonin in cardiac transplant recipients.
Am. J. Cardiol. 84, 1182-1186 (1999)
Abstract

Brown, N. J., Gainer, J. V., Stein, C. M. and Vaughan, D. E.
Bradykinin stimulates tissue plasminogen activator release in human vasculature.
Hypertension 33, 1431-1435 (1999)
Abstract

Chalon, S., Moreno, H., Jr., Hoffman, B. B. and Blaschke, T. F.
Angiotensin-converting enzyme inhibition improves venous endothelial dysfunction in chronic smokers.
Clin. Pharmacol. Ther. 65, 295-303 (1999)
Abstract

Chalon, S., Tejura, B., Moreno, H., Jr., Urae, A., Blaschke, T. F. and Hoffman, B. B.
Role of nitric oxide in isoprenaline and sodium nitroprusside-induced relaxation in human hand veins.
Br. J. Clin. Pharmacol. 47, 91-98 (1999)
Abstract

Dietz, N. M.
Gender and nitric oxide-mediated vasodilation in humans.
Lupus 8, 402-408 (1999)
Abstract

Kato, M., Shiode, N., Teragawa, H., Hirao, H., Yamada, T., Yamagata, T., Matsuura, H. and Kajiyama, G.
The role of nitric oxide in bradykinin-induced dilation of coronary resistance vessels in patients with hypercholesterolemia.
Intern. Med. 38, 394-400 (1999)
Abstract

Kharitonov, S. A., Sapienza, M. M., Chung, K. F. and Barnes, P. J.
Prostaglandins mediate bradykinin-induced reduction of exhaled nitric oxide in asthma.
Eur. Respir. J. 14, 1023-1027 (1999)
Abstract

Leesar, M. A., Stoddard, M. F., Manchikalapudi, S. and Bolli, R.
Bradykinin-induced preconditioning in patients undergoing coronary angioplasty.
J. Am. Coll. Cardiol. 34, 639-650 (1999)
Abstract

Prasad, A., Husain, S. and Quyyumi, A. A.
Abnormal flow-mediated epicardial vasomotion in human coronary arteries is improved by angiotensin-converting enzyme inhibition: a potential role of bradykinin.
J. Am. Coll. Cardiol. 33, 796-804 (1999)
Abstract

Vajo, Z., Szekacs, B., McDonald, M. H., Takahashi, B., Srivathsan, K. and Dachman, W. D.
Paradoxically enhanced bradykinin-induced venodilation in young, healthy, short-term smokers.
J. Cardiovasc. Pharmacol. 34, 316-319 (1999)
Abstract

 

1998

Laine, H., Yki-Jarvinen, H., Kirvela, O., Tolvanen, T., Raitakari, M., Solin, O., Haaparanta, M., Knuuti, J. and Nuutila, P.
Insulin resistance of glucose uptake in skeletal muscle cannot be ameliorated by enhancing endothelium-dependent blood flow in obesity.
J. Clin. Invest. 101, 1156-1162 (1998)
Abstract

Moreno, H., Jr., Chalon, S., Urae, A., Tangphao, O., Abiose, A. K., Hoffman, B. B. and Blaschke, T. F.
Endothelial dysfunction in human hand veins is rapidly reversible after smoking cessation.
Am. J. Physiol. 275, H1040-1045 (1998)
Abstract

 

1997

Ashworth, J. R., Warren, A. Y., Baker, P. N. and Johnson, I. R.
Loss of endothelium-dependent relaxation in myometrial resistance arteries in pre-eclampsia.
Br. J. Obstet. Gynaecol. 104, 1152-1158 (1997)
Abstract

Brown, N. J., Nadeau, J. H. and Vaughan, D. E.
Selective stimulation of tissue-type plasminogen activator (t-PA) in vivo by infusion of bradykinin.
Thromb. Haemost. 77, 522-525 (1997)
Abstract

Doull, J., Sandall, D., Smith, S., Schreiber, J., Freezer, N. J. and Holgate, S. T.
Differential inhibitory effect of regular inhaled corticosteroid on airway responsiveness to adenosine 5' monophosphate, methacholine, and bradykinin in symptomatic children with recurrent wheeze.
Pediatr. Pulmonol. 23, 404-411 (1997)
Abstract

Kato, M., Shiode, N., Yamagata, T., Matsuura, H. and Kajiyama, G.
Coronary segmental responses to acetylcholine and bradykinin in patients with atherosclerotic risk factors.
Am. J. Cardiol. 80, 751-755 (1997)
Abstract

Vajo, Z., McDonald, M., Takahashi, B., Zafar, H., Srivathsan, K. and Dachman, W. D.
Bradykinin-induced venodilation is not different in blacks.
Br. J. Clin. Pharmacol. 44, 285-288 (1997)
Abstract

 

1996

Austin, C. E., Dear, J. W., Neighbour, H., Lund, V. and Foreman, J. C.
The contribution of histamine to the action of bradykinin in the human nasal airway.
Immunopharmacology 34, 181-189 (1996)
Abstract

Brown, N. J., Ryder, D., Gainer, J. V., Morrow, J. D. and Nadeau, J.
Differential effects of angiotensin converting enzyme inhibitors on the vasodepressor and prostacyclin responses to bradykinin.
J. Pharmacol. Exp. Ther. 279, 703-712 (1996)
Abstract

Gainer, J. V., Nadeau, J. H., Ryder, D. and Brown, N. J.
Increased sensitivity to bradykinin among African Americans.
J. Allergy. Clin. Immunol. 98, 283-287 (1996)
Abstract

Marshman, G., Burton, J. L. and Archer, C. B.
Comparison of the actions of kallidin and bradykinin in the skin of normal and psoriatic subjects.
Clin. Exp. Dermatol. 21, 112-115 (1996)
Abstract

Nuutila, P., Raitakari, M., Laine, H., Kirvela, O., Takala, T., Utriainen, T., Makimattila, S., Pitkanen, O. P., Ruotsalainen, U., Iida, H., Knuuti, J. and Yki-Jarvinen, H.
Role of blood flow in regulating insulin-stimulated glucose uptake in humans. Studies using bradykinin, [15O]water, and [18F]fluoro-deoxy-glucose and positron emission tomography.
J. Clin. Invest. 97, 1741-1747 (1996)
Abstract

Ricciardolo, F. L., Geppetti, P., Mistretta, A., Nadel, J. A., Sapienza, M. A., Bellofiore, S. and Di Maria, G. U.
Randomised double-blind placebo-controlled study of the effect of inhibition of nitric oxide synthesis in bradykinin-induced asthma.
Lancet 348, 374-377 (1996)
Abstract

Riccio, M. M. and Proud, D.
Evidence that enhanced nasal reactivity to bradykinin in patients with symptomatic allergy is mediated by neural reflexes.
J. Allergy Clin. Immunol. 97, 1252-1263 (1996)
Abstract

Schaefer, S., Valente, R. A., Laslett, L. J. and Longhurst, J. C.
Cardiac reflex effects of intracoronary bradykinin in humans.
J. Investig. Med. 44, 160-167 (1996)
Abstract