| Process Development
It is highly advisable to first optimize the manufacturing process.This typically results in an economic way to manufacture the product in the quantity and quality desired by our client. Bachem has a team dedicated to such process development work.
Solution phase peptide synthesis
Over 25 large reactors (up to 1400 liters) are dedicated to the synthesis of amino acid derivatives and peptides in solution.
Solid phase peptide synthesis
Over 15 reactors (each at least 75 liters) are dedicated to the solid phase synthesis of peptides
Purification
Large scale counter current distribution, high performance liquid chromatography equipment and conventional chromatography (ion exchange, gel chromatography), are utilized to overcome bottlenecks in large scale purification. Such equipment forms the foundation that allows us to obtain up to 10 kg per lot of highly purified product.
Bachem is committed to the systematic expansion and modernization of its purification equipment in order to ensure the efficient production of multiple kilograms of bulk peptide pharmaceuticals.
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