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New Monograph: Peptides and Diabetes

20. Feb 2012

The new product monograph 'Peptides and Diabetes' gives you an overview of Bachem´s offer of Diabetes-related products.
This revised edition has been enriched with clickable product deeplinks leading directly to the respective products in our Online Shop.

 
According to data from the International Diabetes Federation, more than 250 million people around the world suffer from diabetes mellitus, a chronic metabolic disorder characterized by hyperglycemia. Diabetes mellitus can be divided into two main types, type 1 or insulin-dependent diabetes mellitus (IDDM), and type 2, or non insulin-dependent diabetes mellitus (NIDDM). The absolute lack of insulin, due to destruction of the insulin-producing pancreatic β-cells, is the particular disorder in type 1 diabetes. Type 2 diabetes is mainly characterized by the inability of cells to respond to insulin. The condition affects mostly the cells of muscle and fat tissue, and results in a condition known as „insulin resistance“.
Over time, diabetes mellitus can lead to blindness, kidney failure, and nerve damage. Diabetes mellitus is also an important factor in accelerating the hardening and narrowing of the arteries (atherosclerosis), leading to stroke, coronary heart diseases, and other blood vessel disorders.
Glucose homeostasis is accomplished by complex physiological mechanisms. Control of blood glucose levels involves insulin, glucagon and other peptide hormones such as glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide (GIP)).

 

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