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ANGIOTENSIN II ACETATE 50 µg/VIAL (CLINALFA® BASIC)

Angiotensin II Acetate 50 µg/vial (Clinalfa basic)

U-1050, 4056505

 
Synonym

Ang II

 
Sequence

H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH acetate salt
 

To be used in approved clinical trials only
 
Active Substance

The octapeptide angiotensin II (Ang II) binds to both the AT1 and the AT2 receptors. Ang II interaction with the AT1 receptor results in strong vasoactive effects, the stimulation of aldosterone synthesis and the elevation of blood pressure via direct vasoconstriction of arteriole smooth muscles. The role of the AT2 receptor is not fully understood. Ang II can be metabolized by aminopeptidase into angiotensin III (Ang 2-8) and angiotensin IV (Ang 3-8).

 
Literature References

A considerable number of publications on Clinalfa products used in clinical trials are available. The most important publications are listed here.
 


Note

This product is also available in research grade quality (non GMP)
 

H-1705

Angiotensin II