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GLOSSARY & ABBREVIATIONS

Tnm

Trishydroxymethylnitromethane (ketalized with cyclohexanone)

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Trishydroxymethylnitromethane (which is ketalized with cyclohexanone) represents a lateral amino protecting group, which is removed in two steps. Acidolytic cleavage after Fmoc-SPPS leaves the amino group protected as monocarbamate of tris-hydroxymethyl-nitromethane, which is removed under slightly basic conditions.

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