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GLOSSARY & ABBREVIATIONS

Bom

Benzyloxymethyl

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Benzyloxymethyl (Bom), an acid-labile imidazole protecting group used during Boc-SPPS of His-containing peptides. As an acetal, Bom yields highly reactive formaldehyde upon acid treatment. Thus, Bom is best removed in the presence of Cys, methoxyamine or other compounds reacting with the aldehyde.

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