Europe/Asia USA
Bachem AG Bachem Americas, Inc.
Hauptstrasse 144 3132 Kashiwa Street
4416 Bubendorf - Switzerland Torrance, CA 90505 - USA
Tel +41 61 935 2323 Tel +1 888 422 2436
Fax +41 61 935 2325 +1 888 4BACHEM
E-mail sales.ch@bachem.com +1 310 539 4171
  Fax +1 310 539 9428
  E-mail sales.us@bachem.com

PEPTIDE TRENDS APRIL 2015

Peptide Trends April Edition 2015

MEET US AT TIDES, MAY 3-6, 2015 IN SAN DIEGO, CALIFORNIA

Bachem is participating in TIDES 2015. TIDES provides you with more in-depth case studies, new data presentations and cutting-edge strategies than ever before to help accelerate your product development.

Bachem‘s pipeline contains more than 150 customer projects in (pre)clinical phases. They all have promising potential: in the last two years, a number of products in phase III trials received marketing authorization and phase II projects progressed to phase III clinical trials. Our services include pegylated peptides, peptides for conjugated NCEs and sterile fill and finish (Clinalfa®).

A new service in our portfolio is the selective chemical glycosylation. The technology is applicable to large scale and has the potential to be applied to a variety of peptides, where we can pioneer the concept of improving current and future drugs. We invite you to drop by our booth 210 or you may contact us to schedule a meeting at TIDES

Our Business Development Executives would be glad to present details of our capabilities. We have the capacity to produce peptide APIs in quantities of hundreds of kilograms and small molecules in tens of tons per year.

Our GMP manufacturing facilities are located in Switzerland and the United States and are regularly inspected by the FDA and local authorities.

 

 

PEPTIDE NEWS FRAGMENTS

We search the Internet for news about peptides in basic research and pharmaceutical development. Here are some highlights from recent week:

 

Study to investigate a potential therapy at cellular level for Huntington's disease-EurekAlert!

Opossum-based antidote to poisonous snake bites could save thousands of lives-ACS

Drug re-engineered to improve surgery safety-GEN

 

Thin transparent flexible screens: Roll up your screen and stow it away?-ScienceDaily

PEPTIDE PUZZLER

Win a battery charger
Dr, Andrea Calderan

Glyco Peptides: How many glycans are available for modifying your peptide?

 

A.) 5

B.) 15

C.) > 50

 

Don`t tell anyone, here is a little >>hint 

 

Rules

 

Submit the correct answer to puzzle@bachem.com by 12:01 am Los Angeles time on Monday, May 18, 2015 for your chance to win a Bachem mobile battery pack. 

 

 

Last Month's Winner

 

Congratulations to Dr. Andrea Calderan!

Andrea is since 1984 a scientist researcher at the Padova unit of the Institute of Biomolecular Chemistry of the Italian National Research Council. His scientific interests involve the study of peptides and proteins, with the aim of determining the relationship between the biological activity and the secondary structure of natural or synthetic molecules. In particular, he has a considerable experience in the field of peptide chemistry, dealing mainly of chemical synthesis (in solid- and liquid-phase) of biologically active peptides and their conformational characterization, using different techniques (fluorescence, circular dichroism, IR, NMR).

 

 

LATEST LITERATURE CITINGS

Bachem peptides and biochemicals are frequently cited in research publications. View a selection of recent articles that cite Bachem peptides.

 

- V.D. Ramseyer et al., Angiotensin II-induced hypertension blunts thick ascending limb NO production by reducing NO synthase 3 expression and enhancing threonine 495 phosphorylation. Am. J. Physiol. Renal Physiol. 308, F149-F156 (2015) [Abstract]

- M. Labeur et al., TMEFF2 is an endogenous inhibitor of the CRH signal transduction pathway. J. Mol. Endocrinol. 54, 51-63 (2015) [Abstract]

- K. Lin et al., In vivo radioimaging of bradykinin receptor B1, a widely overexpressed molecule in human cancer. Cancer Res. 75, 387-393 (2015) [Abstract]

- H. Yang et al., A+-Helix of protein C inhibitor (PCI) is a cell-penetrating peptide that mediates cell membrane permeation of PCI. J. Biol. Chem. 290, 3081-3091 (2015) [Abstract]

- D. Vatner et al., Insulin-independent regulation of hepatic triglyceride synthesis by fatty acids. PNAS. 112, 1143-1148 (2015) [Abstract]