Product Datasheets
Our product data sheets contain detailed information on our generic APIs and their specifications.
AntazolineThe histamine H1 receptor antagonist antazoline, an imidazoline derivative, acts as an antihistamine and, hence, as an anti-allergic agent. As antazoline itself is not sufficiently soluble in water, a number of salts of the base with biocompatible strong acids are in use as active substances. In ophthalmic solutions, usually in combination with a decongestant, they are applied topically to relieve the symptoms of allergic conjunctivitis. |
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Buserelin Ph. Eur.H-4224-GMP, 4038785 Buserelin is a potent synthetic agonist of the luteinizing hormone-releasing hormone (LHRH), also called gonadotropin-releasing hormone (GnRH). Administration of buserelin results in an initial increase of luteinizing hormone (LH) levels, serum testosterone levels in males, and serum estradiol levels in females. This is followed by a sustained inhibition of gonadotropin release from the pituitary, suppression of ovarian and testicular steroidogenesis, and reduced circulating levels of gonadotropin and gonadal steroids. Buserelin is indicated for the treatment of hormone-dependent prostate cancer, endometriosis, uterine myoma, precocious puberty, and infertility. |
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Calcitonin (salmon) Ph. Eur.H-2260-GMP, 4013234 Calcitonin is a peptide hormone involved in calcium and phosphorus homeostasis. Its inhibitory effect on osteoclast activity lowers blood calcium levels and positively influences bone mass density. Calcitonin (salmon) is more potent than the human homolog and is indicated for the treatment of osteoporosis, Paget‘s disease, hypercalcemia, and reflex sympathetic dystrophy. |
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Deslorelin High AcetateH-4116-GMP, 4027311 Deslorelin High Acetate is a synthetic nonapeptide analog of the natural gonadotropin-releasing hormone (GnRH) or luteinizing hormone-releasing hormone (LHRH). Short-term administration of deslorelin results in a stimulation of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) levels followed by an increase in testosterone and estradiol synthesis. Prolonged administration causes a sustained down-regulation of circulating LH and FSH levels and suppression of testicular and ovarian steroidogenesis. The stimulatory effect of deslorelin on LH secretion is indicated for the induction of ovulation in estrous mares. Deslorelin is also used as a contraceptive for male dogs. |
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GlucagonH-6790-GMP, 4015466 Glucagon is a polypeptide hormone secreted by the alpha cells of the islets of Langerhans in the pancreas. The key biological actions of glucagon converge on regulation of glucose homeostasis through enhanced synthesis and mobilization of glucose in the liver. It represents the counterregulatory hormone, opposing the action of insulin. Glucagon has diverse utility both as a therapeutic and diagnostic agent. |
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Gonadorelin Acetate Ph. Eur.H-4005-GMP, 4008614 Gonadorelin, also known as luteinizing hormone-releasing hormone (LHRH) or gonadotropin-releasing hormone (GnRH), is a hypothalamic decapeptide hormone which induces the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the anterior pituitary. Its pulsatile release is crucial for proper development and reproductive functions. Administration of Gonadorelin Acetate is indicated for the diagnosis of hypogonadotropic hypogonadism and the treatment of hypothalamic amenorrhea, male hypogonadotropic hypogonadism, and cryptorchism. |
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Goserelin Acetate Ph. Eur.H-6395-GMP, 4036062 Goserelin Acetate is a potent synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH), also called gonadotropin-releasing hormone (GnRH). It acts as an LHRH agonist. Administration of Goserelin Acetate results in an initial increase of luteinizing hormone (LH) levels and in increases of serum testosterone levels in males and serum estradiol levels in females. This is followed by a decrease in serum LH levels and suppression of testosterone or estradiol. Goserelin Acetate is indicated for treatment of hormone-dependent breast and prostate cancer, endometriosis, uterine myoma, and for use in reproductive medicine. |
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Histrelin AcetateH-9210-GMP, 4010113 Histrelin Acetate is a synthetic nonapeptide analog of the luteinizing hormone-releasing hormone (LHRH), also known as gonadotropin-releasing hormone (GnRH). In single doses, it stimulates the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the anterior pituitary. Long-term treatment causes pituitary desensitization followed by a reduction in LH and FSH secretion. The resulting suppression of gonadal sex steroid biosynthesis can be utilized in the treatment of central precocious puberty. |
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Leuprolide Acetate Ph. Eur.H-4060-GMP, 4008634 Leuprolide Acetate is a luteinizing hormone-releasing hormone (LHRH) agonist. Continuous administration of Leuprolide Acetate results in a down-regulation of circulating luteinizing hormone (LH) and follicle-stimulating hormone (FSH) levels followed by an inhibition of testosterone and estradiol synthesis. The suppressive effect on gonadal steroid concentrations is used in the treatment of hormone-dependent prostate and breast cancer, endometriosis, and central precocious puberty. |
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Protirelin Ph. Eur.H-4915-GMP, 4003036 Protirelin is a synthetic tripeptide with the primary structure L-pyroglutamyl-L-histidyl-L-proline amide and corresponds to thyroliberin, also known as thyrotropin-releasing hormone (TRH). Produced in the paraventricular nucleus of the hypothalamus, TRH stimulates the release of thyroid-stimulating hormone (TSH, thyrotropin) from the anterior pituitary and therefore plays a central role in the regulation of the hypothalamic-pituitary-thyroid (HPT) axis. Administration of protirelin is indicated for the diagnostic assessment of thyroid function. |
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