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Bachem AG Bachem Americas, Inc. Bachem Japan K.K.
Hauptstrasse 144 3132 Kashiwa Street AREA Shinagawa, 13F
4416 Bubendorf - Switzerland Torrance, CA 90505 - USA Tokyo 108-0075 - Japan
Tel +41 58 595 2021 Tel +1 888 422 2436 Tel +81 3 4405 3141
Fax +41 58 595 2040 Tel +1 888 4BACHEM Email sales.jp@bachem.com
Email sales.ch@bachem.com Fax +1 310 539 9428  
  E-mail sales.us@bachem.com  

PRODUCT FLYERS

Bachem offers for free a series of flyers on selected groups of products in peptide research.

Flyers

Cyclic Peptides
Variants of custom peptide cyclization available from Bachem
 
Our customers can choose from various approaches for obtaining cyclic peptides.
 
A wealth of cyclic peptides has been isolated from natural sources. The compounds show an amazing structural diversity. Cyclization of peptides is as well an important tool for structure-activity studies and drug development. As ring formation limits the flexibility of the peptide chain, it allows inducing or stabilizing active conformations. Moreover, cyclic peptides are less sensitive to enzymatic degradation. The broad choice of cyclization variants leaves much room for optimizing the properties of a cyclopeptide. Numerous chemistries together with the required amino acid derivatives are at hand for ring closure.
(pdf, 183 KB)
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Di- and Tripeptides
For modified tripeptides, tripeptide substrates, and our complete range of research peptides please visit shop.bachem.com
(pdf, 667 KB)
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Fluorescent Peptides and Amino Acids
We offer peptides and amino acids tagged with Tide FluorTM fluorescent dyes. They meet highest demands in fluorescence intensity and photo-stability, and outperform most conventional and proprietary dyes for these properties. For optimum results in FRET, Tide FluorTM dyes should be combined with Tide QuencherTM acceptors.
(pdf, 1 MB)
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Fmoc-Amino Acids
We are pleased to present a compilation of standard Fmoc-amino acid derivatives available from Bachem.
(pdf, 540 KB) Bachem
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GPCR Ligands
The G protein-coupled receptors fall into 6 classes. The largest group (class A) includes the rhodopsin-like receptors followed by class B the secretin-like receptors and the metabotropic glutamate/pheromone receptor family (class C). A large number of class A and B receptors are activated by peptides or proteins. We are pleased to present a choice of our GPCR-binding peptides, receptor agonists and antagonists.
(pdf, 140 KB) Bachem
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Gastrointestinal Research
The gastrointestinal tract is the source of a multitude of peptide hormones such as cholecystokinin, gastrin, glucagon, motilin, secretin, and somatostatin. They result from the processing of precursor proteins expressed by specialized cells. Most of these hormones exhibit multiple activities. They regulate food uptake and the digestive system as well as vital processes involving other organs. Hence, dysregulation of their production is involved in numerous diseases. Bachem offers these hormones together with peptide-based agonists and antagonists. For our complete range of peptides, amino acid derivatives, and biochemicals please visit shop.bachem.com
(pdf, 394 KB)
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HFIP-treated Amyloids
Amyloid peptides are prone to aggregation. Treating amyloid β-peptides with 1,1,1,3,3,3-hexafl uoroisopropanol (HFIP) is the standard method for disrupting amyloid fi brils and generating the Aβ monomers. Removal of this volatile solvent leaves fi lms of disaggregated peptides which can be reconstituted in DMSO, double-distilled water, or buffers for further studies (please see reverse side for a compilation of literature references)
(pdf, 3 MB) Bachem
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Histone Peptides
We are pleased to present our newly available histone peptides for epigenetics research.
(pdf, 115 KB)
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Impurities in Peptide APIs
Impurities observed in peptide APIs can be process related impurities, which cannot be removed completely during purification of the crude peptide or product related impurities that are formed as degradation products during storage. Typically these impurities are byproducts resulting from side reactions occurring during the syntheses, such as racemization, deamidation, oxidation or aspartimide formation. Peptide APIs obtained by solid-phase synthesis may additionally contain analogs resulting from deletion or double insertion of amino acids. References of such compounds are needed for analytical method development and release testing, because fulfilling the specifications for byproducts is required by the relevant pharmacopeia and, most importantly, for ensuring the quality of the API.
(pdf, 215 KB)
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Infectious Diseases
We are pleased to present a selection of peptides, substrates, and inhibitors for use in research on infectious viruses.
(pdf, 341 KB) Bachem
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