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Bachem AG Bachem Americas, Inc.
Hauptstrasse 144 3132 Kashiwa Street
4416 Bubendorf - Switzerland Torrance, CA 90505 - USA
Tel +41 61 935 2323 Tel +1 888 422 2436
Fax +41 61 935 2325 +1 888 4BACHEM
E-mail sales.ch@bachem.com +1 310 539 4171
  Fax +1 310 539 9428
  E-mail sales.us@bachem.com

PRODUCT FLYERS

Bachem offers for free a series of flyers on selected groups of products in peptide research.

Flyers

New Building Blocks
We are pleased to present the latest additions to our broad offer of amino acid derivatives and products for peptide synthesis.
(pdf, 819 KB) Bachem
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New Peptides
We are pleased to present the latest additions to our broad offer of research peptides.
(pdf, 227 KB)
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Obesity Research
We are pleased to present a selection of our products for obesity research. Obesity has turned into one of the greatest health care challenges. Factors influencing body weight as food consumption, energy expenditure and glucose homeostasis are regulated by peptide hormones, many of them produced in the gastrointestinal tract. Together with their agonists and antagonists, they are important research tools.
(pdf, 434 KB)
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Osteoporosis Research
We are pleased to present a selection of our products for research in bone diseases. The formation, growth, mineralization, and metabolization of bones is regulated by hormones. Many of them are peptides. Calcitonin, parathyrin (pTH), and pTH-related protein (pTHrP) and their analogs have been evaluated as drugs for managing bone diseases such as osteoporosis, a condition becoming a major challenge with an aging population. Each year the disease is leading to approximately 9 million bone fractures. According to estimates of the International Osteoporosis Foundation more than 200 million people worldwide are affected by osteoporosis.
(pdf, 431 KB)
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Parkinson & MS
We are pleased to present a selection of our products for Parkinson’s disease and multiple sclerosis research. Parkinson’s disease (PD) and multiple sclerosis (MS) range among the neurodegenerative disorders for which effective drugs are still lacking. Both are chronic diseases with unpredictable course causing progressive physical disability and cognitive decline, and broadly affecting the patient’s life. Up to now, therapies can only slow their progression and ameliorate the quality of life of the affected patients. For MS research, experimental autoimmune encephalomyelitis (EAE) has been developed as an animal model.
(pdf, 579 KB)
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Pegylation of Peptides
PEGylation signifies the usually covalent attachment of polyethylene glycol chains to peptides, proteins, or antibodies used as pharmaceuticals. PEGylation allows to improve the pharmacologic properties of the drug, e.g., by increasing half-life, improving solubility, and reducing immunogenicity and antigenicity.
(pdf, 200 KB)
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Periodic Chart of Amino Acids
We are pleased to present our Periodic Chart of Amino Acids.
(pdf, 544 KB)
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Pituitary Peptides
A selection of our peptidic pituitary and hypothalamic hormones, analogs, agonists and antagonists.
(pdf, 406 KB)
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Post-translational Modifications (PTMs)
We are pleased to present a selection of our building blocks for the synthesis of PTM peptides and proteins. Post-translational modifications (PTMs) enable the cell to change the properties and activities of proteins after expression. Most of the PTMs are catalyzed by specialized enzymes. Practically all proteinogenic amino acids can be modified, thus PTMs considerably increase the diversity of protein structures. PTMs generate or eliminate charged moieties and thus changes the pI of a protein, e.g. by Ophosphorylation or Nε-acetylation of Lys. N-Acetylation and N-methylation of histones are tools for regulating DNA transcription, they can be reverted. Non-enzymatic PTMs can be an indication of “aging” of proteins or pathological processes.
(pdf, 129 KB)
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Pseudoproline Dipeptides
Ser and Thr pseudoproline dipeptides play a crucial role in Fmoc-SPPS. The corresponding Cys derivatives broaden the scope of pseudoproline application, especially as cysteine can be desulfurated yielding alanine. 2,4-dimethoxyphenyl(Dmp)- thiaproline is compatible with standard Fmoc/tBu protocols and can be cleaved with 80% TFA in DCM. Our serine- and threonine-derived pseudoproline dipeptides are available in 5 g, 10 g, and 25 g-packs. For larger amounts, please ask for a quote.
(pdf, 139 KB)
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