Antazoline Phosphate

Q-2695-GMP, 4045162

Bachem Regulatory Documentation

DMF

Synonyms

2-(N-Phenyl-N-benzyl-aminomethyl)imidazoline · phosphate;
2-[(N-Benzylanilino)methyl]-2-imidazoline · phosphate;
4,5-Dihydro-N-phenyl-N-(phenylmethyl)-1H-imidazole-2-methanamine · phosphate

Fields of Application

Conjunctivitis

Active Substance

The histamine H1 receptor antagonist antazoline, an imidazoline derivative, acts as an antihistamine and, hence, as an antiallergic agent. In ophthalmic solutions, usually in combination with a decongestant, antazoline phosphate is applied topically to relieve the symptoms of allergic conjunctivitis.

Molecular Information

Molecular Formula

C17H19N3 · H3PO4

Relative Molecular Mass

265.36 g/mol (net), 363.35 g/mol (phosphate)

CAS-Number

91-75-8 (net), 154-68-7 (phosphate)

Long-term Storage

5 ± 3 °C