(Arg8) - Vasopressin

(Arg8)-Vasopressin

4077849

Bachem Regulatory Documentation

DMF

Synonyms

Argipressin; AVP; Arginine Antidiuretic Hormone; Leiormone

Sequence

H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH₂ (Disulfide bond)

Fields of Application

Central diabetes insipidus
Variceal bleeding
Vasoconstrictor in local anaesthetic injections

Active Substance

(Arg8)-Vasopressin or argipressin is an antidiuretic peptide hormone that plays a key role in maintaining plasma osmolality. The peptide released from the posterior pituitary gland promotes renal tubular reabsorption of water.
In high concentration, it also raises blood pressure by inducing moderate vasoconstriction.
Argipressin is involved in the control of circadian rhythm, thermoregulation, and ACTH release in the brain.

Molecular Information

Molecular Formula

C46H65N15O12S2

Relative Molecular Mass

1084.25 g/mol

CAS-Number

113-79-1 (net)

Long-term Storage

-20 ± 5°C