Desmopressin Acetate

H-7675-GMP, 4033038

Bachem Regulatory Documentation

CEP, DMF

Synonyms

DDAVP; (Deamino-Cys1,D-Arg8)-Vasopressin

Sequence

3-Mercaptopropionyl-Tyr-Phe-Gln-Asn-Cys-Pro-D-Arg-Gly-NH2 acetate salt (Disulfide bond)

Fields of Application

Nocturnal enuresis
Central diabetes insipidus, polyuria, polydipsia
Mild and moderate forms of hemophilia A and von Willebrand disease

Active Substance

Desmopressin (DDAVP) is a synthetic analog of vasopressin with low vasopressor activity. Apart from its increasing effect on water resorption by the kidneys, desmopressin raises plasma levels of von Willebrand factor and factor VIII.

In veterinary medicine, desmopressin is applied in the treatment of canine and feline diabetes insipidus.

Molecular Information

Molecular Formula

C46H64N14O12S2

Relative Molecular Mass

1069.23 g/mol

CAS-Number

16679-58-6 (net), 62288-83-9 (acetate), 62357-86-2 (acetate trihydrate)

Long-term Storage

-20 ± 5°C