Etomidate

2990-GMP, 4049295

Bachem Regulatory Documentation

CEP, DMF

Synonyms

1-[(1R)-1-Phenylethyl]-1H-imidazole-5-carboxylic acid ethyl ester;
(+)-Ethyl 1-(α-methylbenzyl)imidazole-5-carboxylate

Fields of Application

Anesthesia

Active Substance

The imidazole derivative etomidate is a rapid, short acting intravenous anesthetic agent. Etomidate, a GABA-A receptor agonist, acts as a sedative but not as an analgesic. A relative lack of significant hemodynamic and respiratory effects is a further reason for choosing etomidate for inducing anesthesia. Etomidate is applied as a sedative or anesthetic especially in emergency medicine. The anesthetic has also found use in small animal veterinary practice.

Molecular Information

Molecular Formula

C14H16N2O2

Relative Molecular Mass

244.29 g/mol

CAS-Number

33125-97-2

Long-term Storage

Room temperature