Glucagon
H-6790-GMP, 4143597
Bachem Regulatory Documentation
DMF
Sequence
H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH
Fields of Application
Hypoglycemia (diabetes mellitus)
Active Substance
Glucagon is produced in the α-cells of the islets of Langerhans. The hormone opposes the action of insulin. Glucagon promotes the synthesis and mobilization of glucose from glycogen in the liver. The generation of glucose from lipids is regulated by glucagon as well.
Additionally, glucacon induces inotropic and chronotropic effects by raising the concentration of cAMP.
Molecular Information
Molecular Formula
C153H225N43O49S
Relative Molecular Mass
3482.80 g/mol
CAS-Number
16941-32-5
Long-term Storage
-20 ± 5°C