Bachem Regulatory Documentation
GnRH; Gonadotropin-Releasing Hormone; LHRH; Luliberin;
Luteinizing Hormone-Releasing Factor
Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 acetate salt
Fields of Application
Ovarian follicular cysts (veterinary medicine)
Use in reproduction medicine
Diagnosis of the hypothalamic-pituitary-gonadal axis function
Synchronization of ovulation (veterinary medicine)
Gonadorelin, also known as GnRH or LHRH, is produced by neuroendocrine cells within the hypothalamus. The hormone is secreted pulsatilely. Gonadorelin induces the release of LH and FSH from the anterior pituitary.
After a transient increase, continuous administration of gonadorelin results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.
Relative Molecular Mass
33515-09-2 (net), 34973-08-5 (acetate)
-20 ± 5°C