Goserelin Acetate

CEP, DMF

(D-Ser(tBu)6,Azagly10)-LHRH

Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-Azagly-NH2
acetate salt

Advanced hormone-dependent prostate cancer
Advanced hormone-dependent breast cancer
Endometriosis
Uterine myoma
Use in reproductive medicine

Goserelin Acetate is a potent GnRH (LHRH) agonist. After a transient increase, continuous administration of goserelin results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.

Molecular Formula

C₅₉H₈₄N₁₈O₁₄

Relative Molecular Mass

1269.43 g/mol

CAS-Number

65807-02-5 (net), 145781-92-6 (acetate)

Long-term Storage

-20 ± 5°C

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