Goserelin Acetate
4141427
Bachem Regulatory Documentation
CEP, DMF
Synonyms
(D-Ser(tBu)6,Azagly10)-LHRH
Sequence
Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-Azagly-NH2
acetate salt
Fields of Application
Advanced hormone-dependent prostate cancer
Advanced hormone-dependent breast cancer
Endometriosis
Uterine myoma
Use in reproductive medicine
Active Substance
Goserelin Acetate is a potent GnRH (LHRH) agonist. After a transient increase, continuous administration of goserelin results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.
Molecular Information
Molecular Formula
C59H84N18O14
Relative Molecular Mass
1269.43 g/mol
CAS-Number
65807-02-5 (net), 145781-92-6 (acetate)
Long-term Storage
-20 ± 5°C