pTH (1-34) (human) Acetate
H-4835-GMP, 4158068
Bachem Regulatory Documentation
DMF
Synonyms
Parathyroid hormone (1-34) (human)
Sequence
H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH acetate salt
Fields of Application
Diagnosis of hypoparathyroidism
Active Substance
pTH (1-34) (human) corresponds to N-terminal part of human parathyroid hormone, a peptide consisting of 84 amino acids. pTH (1-34) (human) shows the same activity and pharmacological profile as the native peptide hormone.
Intermittent administration of pTH (1-34) (human) acetate in low dosage stimulates bone formation and increases bone mineral density.
Bachem’s pTH (1-34) (human) is obtained by chemical synthesis.
Molecular Information
Molecular Formula
C181H291N55O51S2
Relative Molecular Mass
4117.77 g/mol
CAS-Number
52232-67-4 (net), 99294-94-7 (acetate)
Long-term Storage
-20 ± 5°C