pTH (1-34) (human) Acetate

H-4835-GMP, 4033364

Bachem Regulatory Documentation

DMF

Synonyms

Parathyroid hormone (1-34) (human)

Sequence

H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH acetate salt

Fields of Application

Osteoporosis – not yet an approved application
Diagnosis of hypoparathyroidism

Active Substance

pTH (1-34) (human) corresponds to N-terminal part of human parathyroid hormone, a peptide consisting of 84 amino acids. pTH (1-34) (human) shows the same activity and pharmacological profile as the native peptide hormone.
Intermittent administration of pTH (1-34) (human) acetate in low dosage stimulates bone formation and increases bone mineral density.
Bachem’s pTH (1-34) (human) is obtained by chemical synthesis.

Molecular Information

Molecular Formula

C181H291N55O51S2

Relative Molecular Mass

4117.77 g/mol

CAS-Number

52232-67-4 (net), 99294-94-7 (acetate)

Long-term Storage

-20 ± 5°C