Somatostatin

H-1490-GMP, 4006075

Bachem Regulatory Documentation

CEP

Synonyms

Somatostatin-14; SRIF-14;
Somatotropin Release-Inhibiting Factor; SRIF

Sequence

H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH acetate salt (Disulfide bond)

Fields of Application

Ulcer bleeding
Hemorrhagic gastritis
Postoperative pancreatic and duodenal fistulae
Variceal hemorrhage

Active Substance

Somatostatin (SRIF) is an inhibitor of growth hormone release from the anterior pituitary and hence an antagonist of GRF. Somatostatin suppresses the release of a variety of other hormones involved in the regulation of important physiological functions of the gastrointestinal tract. Somatostatin also inhibits TSH production.

Molecular Information

Molecular Formula

C76H104N18O19S2

Relative Molecular Mass

1637.90 g/mol

CAS-Number

38916-34-6 (net)

Long-term Storage

-20 ± 5°C