Somatostatin
H-1490-GMP, 4006075
Bachem Regulatory Documentation
CEP
Synonyms
Somatostatin-14; SRIF-14;
Somatotropin Release-Inhibiting Factor; SRIF
Sequence
H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH acetate salt (Disulfide bond)
Fields of Application
Ulcer bleeding
Hemorrhagic gastritis
Postoperative pancreatic and duodenal fistulae
Variceal hemorrhage
Hemorrhagic gastritis
Postoperative pancreatic and duodenal fistulae
Variceal hemorrhage
Active Substance
Somatostatin (SRIF) is an inhibitor of growth hormone release from the anterior pituitary and hence an antagonist of GRF. Somatostatin suppresses the release of a variety of other hormones involved in the regulation of important physiological functions of the gastrointestinal tract. Somatostatin also inhibits TSH production.
Molecular Information
Molecular Formula
C76H104N18O19S2
Relative Molecular Mass
1637.90 g/mol
CAS-Number
38916-34-6 (net)
Long-term Storage
-20 ± 5°C