Triptorelin Acetate

H-4075-GMP, 4008442

Bachem Regulatory Documentation

DMF

Synonyms

(D-Trp6)-LHRH; (D-Trp6)-GnRH

Sequence

Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 acetate salt

Fields of Application

Advanced hormone-dependent prostate cancer
Use in reproduction medicine
Endometriosis
Central precocious puberty

Active Substance

Triptorelin Acetate is a potent LHRH (GnRH) agonist. After a transient increase, continuous administration of triptorelin acetate results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.

Molecular Information

Molecular Formula

C64H82N18O13

Relative Molecular Mass

1311.47 g/mol

CAS-Number

57773-63-4 (net), 140194-24-7 (acetate)

Long-term Storage

-20 ± 5°C

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