GLUCAGON

Glucagon

H-6790-GMP, 4015466
 

Bachem Regulatory Documentation

DMF

Sequence

H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH

Fields of Application

Hypoglycemia (diabetes mellitus)

Active Substance

Glucagon is produced in the α-cells of the islets of Langerhans. The hormone opposes the action of insulin. Glucagon promotes the synthesis and mobilization of glucose from glycogen in the liver. The generation of glucose from lipids is regulated by glucagon as well.
Additionally, glucacon induces inotropic and chronotropic effects by raising the concentration of cAMP.