In 2021, Bachem acquired the first two process-scale Multicolumn Counter-current Solvent Gradient Purification (MCSGP) systems for the purification of peptides and oligonucleotides. The systems are qualified for GMP use for which first purifications at scale were successfully performed. In this webinar, our efforts to establish large-scale MCSGP will be presented, starting from initial small-scale experiments in 2017 to the first large-scale API purification in 2022. Besides showing real data from process development and manufacturing, we will provide insights regarding potential control strategies as well as the general workflow for process-scale MCSGP purification of large synthetic molecules.
ICal and gCal can be downloaded at the bottom of this page.
Process Manager Chromatography and Technology Transfer Oligo at Bachem
Ralf joined Bachem AG in 2008. Over the last decade, he held several positions at Bachem: ranging from process development to leading the large-scale purification of peptides at the Bubendorf site. In his current position as Process Manager Chromatography and Technology Transfer, he is focusing on innovative purification technologies and processes.
Business Development Manager at Bachem
Keith has more than ten years of research and development experience in the field of solid-phase peptide synthesis (SPPS) and spent most of his career striving to improve this technique. SPPS. In 2021, he joined Bachem as Business Development Manager and resides outside of Charlotte, NC. Keith published several papers during his career and enjoys traveling, networking, and presenting novel research work at conferences and symposiums around the world.
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