Brain natriuretic peptide (BNP) is a natriuretic, diuretic and vasodilatory factor that is secreted by the brain and the heart atria.

t-Butyloxycarbonyl (Boc) is an acid-labile temporary Nα-protecting group employed in solution synthesis and in SPPS (Boc/Bzl-based SPPS). Common cleavage reagents are TFA/methylene chloride (1:1), HCl in ethyl acetate or dioxane, 98% formic acid.