3-Methylpent-3-yl ester (OMpe), an acid-labile carboxy-protecting group used for Asp in Fmoc-SPPS. This sterically more demanding analog of the t-butyl ester has been developed especially for reducing base-catalyzed aspartimide formation.
Mar 18, 2021
3-Methylpent-3-yl ester (OMpe), an acid-labile carboxy-protecting group used for Asp in Fmoc-SPPS. This sterically more demanding analog of the t-butyl ester has been developed especially for reducing base-catalyzed aspartimide formation.
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