Knowledge Hub 
Knowledge Hub
Case study: Verification of SAX method selectivity using 2D-LC-MS for peak purity assessment of oligonucleotide APIs
Accurate analytical characterization is essential throughout oligonucleotide development, supporting impurity profiling, stability assessment, and ultimately the delivery of…
API contract manufacturing: Process, benefits, and partner selection
Manufacturing active pharmaceutical ingredients (APIs) is a complex undertaking that requires specialized process knowledge, advanced manufacturing capabilities, and…
What is Tag-Assisted Peptide Synthesis (TAPS)?
As the leading peptide manufacturer, Bachem is at the forefront of innovative synthesis methods. One cutting-edge approach is…
A mild and sustainable platform for disulfide bond formation in peptide manufacturing using dehydroascorbic acid
Disulfide bond formation is a key step in the manufacture of cysteine‑containing peptides, yet established oxidation…
Stirring Things Up: Integrating Stirred-Bed SPOS and Enzymatic Ligation for Industrial Oligonucleotide Production
The rising demands for therapeutic oligonucleotides requires scalable, efficient, and more sustainable manufacturing solutions. Stirred bed…
