MORE THAN 5000 PRODUCTS AVAILABLE!

Our catalog products are sold from stock in various pack sizes or in larger quantities and can be purchased via our Online Shop. Most of them are manufactured in St. Helens, UK or Bubendorf, Switzerland. Catalog products may only be used for laboratory and research purposes. They must not be used in humans. The products of the main catalog are divided into two categories. The section “Amino Acids and Biochemicals” contains amino acid derivatives and products for the synthesis of peptides as well as a plurality of biochemicals. These products are mainly ordered by chemists, but also serve customers involved in biological and medical research. The section “Peptides” includes all peptides and small proteins and is dedicated mainly to life sciences and biomedical research.

Our catalog offering is impressive and probably the largest in the world. The portfolio is tuned to fulfill the needs of modern scientists in fields, such as chemistry, biology and medicine. Our catalog covers a large range of areas, such as

• Alzheimer’s Disease Peptides
• Antimicrobial Peptides
• Peptides for Cancer Research
• Cell-permeable Peptides (CPP)
• Diabetes Peptides
• Amino Acid Derivatives, Resins, Linkers & Reagents

All products made by Bachem fulfill the highest standards in quality and product reliability.

Benefits

It is our pleasure to introduce our online shop with enhanced functionality for order placement and quote generation. You will benefit from savings by placing your orders online and the discount program for catalog products is now even more attractive than before. In addition, we are quick: Your order usually is shipped within one to two business days out of our distribution centers in the USA and in Europe.

Multiple Discounts

In our Online Shop, discounts can be applied and accumulated. Please benefit from our

• Online Order Discount (7 %)
• Multiple Vial Discount 
      – 2 vials (5 % discount)
      – 3 to 5 vials (10 % discount)
      – 6 to 9 vials (15 % discount)
      – 10 to 30 vials (20 % discount)
      – ≥ 31 vials (25 % discount)

Moreover, we offer discounts for large quantities of a product (bulk). The minimum amount required for bulk discount is fivefold the largest pack.

Instant Quote Generation

Our newest feature allows you to compile your individual quotations, including all applicable discounts. Create and convert quotations in our Online Shop with just a few clicks!

Quick Access to Information

A lot of valuable information is presented alongside with the products and can be downloaded or opened as links. For example, you will find

• product availability
• lot-specific analytical data sheets (ADS)
• safety data sheets (MSDS; according to 1907/2006/EC, Article 31)
• product-specific literature references
• links to related products.

Furthermore, you can take advantage from a lot of additional product data such as CAS Registry Number, one letter code, areas of scientific interest and many more. If you require further support, please do not hesitate to chat with us online via our chat box.

Enter Product-Related Search Terms

The text search in our Online Shop is reliable and quick. Not only product names can be found, but also any other stored information, and the latter is regularly updated. You can find your product by searching

• product names
• sequences (one letter or three letter code)
• synonyms or key words
• CAS numbers
• product numbers
• molecular formulas.

Shop by Filters

You can filter the search results for• new products
• dye label
• product families & subfamilies
• salt forms
• molecular mass (using a selector)
• source (synthetic or recombinant).

Browse Main Categories

Our Online Shop is sub-divided into four main categories.

Application

The products are clustered by specific areas of scientific interest. If you open for example the Application Alzheimer’s Disease, Cancer Research or Cell-permeable Peptides, you will find all of our products directly related to these fields. The Application might be further divided into sub-areas, for example Tau Peptides in the Application Alzheimer’s Disease.

Inhibitors and Substrates

You will find a wide range of enzymes, for which we offer inhibitors and substrates right from stock. The products are sub-divided into inhibitors and substrates, respectively, for each specific enzyme.

Amino Acids and Biochemicals

This category contains all of our non-peptide products, such as amino acids, amino acid derivatives, resins, linkers and biochemicals. This is also regardless of whether they are already contained in Application or Inhibitors and Substrates. You will also find a number of very special products like the α-Methyl Amino Acids “by Dottikon” as well as products, for which Bachem is the exclusive supplier.

Peptides

This category contains all peptides, offered in our catalog, regardless of whether they are already contained in Application or Inhibitors and Substrates. The peptides cover an impressive range of research fields and are sub-divided into families and sub-families, oriented on the type of peptide.

Please visit our Online Shop.

TECHNICAL LIBRARY

Benefit from a Wealth of Information

Bachem wants to provide the best possible information and offers a wide range of documentation and practical information on our various products and services. Our FAQ section provides you with answers to numerous questions you may have concerning the world of peptides. You can also download any document from our technical library. The information is updated by our Science Team on a regular basis. Some of the documents are also available in Chinese, Japanese, Spanish or Portuguese language.

Selection of Documents for Download

The Technical Library at our homepage is divided into document classes.

Catalogs and Brochures

Our catalogs and brochures present peptides for research and products for peptide synthesis, collated by specific topics or applications. You also find information about our offer of generic API and related services to the pharma and biotech industries. In addition, you can order our desired print catalogs, which we, after a brief registration of your contact details and affiliation, will send cost-free to you.

Product Monographs

Our Product Monographs are the first choice, if you are searching for profound scientific or technical information towards a certain field or research topic. Almost like a scientific review, the Monographs summarize in a couple of pages basic information and the latest proceedings. The Product Monographs contain regularly updated lists of relevant Bachem products, which help you to find the best-suited peptides, amino acids or biochemicals.

Product Flyers

Our Product Flyers typically are dedicated to a particular class or family of products and contain regularly updated product lists. The scientific description can range from a brief product summary to deeper going background information. In addition, you can find very useful overview posters like our Chart of Unusual Amino Acids, Poster of Di- and Tripeptides or Periodic Chart of Amino Acids.

Scientific Posters

In this section, you can download scientific posters from our participations at various meetings.

Technical Notes

Take advantage of lots of useful facts on Bachem products.

Please visit our Technical Library.

Peptides are making an impact in a wide range of applications including Alzheimer’s disease, diabetes, cancer and the treatment of infections. Chemists have applied innovative approaches to peptides in order to broaden their applicability as therapeutics. For example, the clinical pipeline of peptides includes peptides with more than one pharmacological activity such as dual agonists or multiple biological functions such as antimicrobial peptides that heal wounds and stimulate the immune system. In addition, there is an increase in the development of oral formulations that offer increased patient compliance and ease of administration.

Alzheimer’s disease

AD is a global concern with an estimated 50 million people living with AD or other dementias worldwide. An increasing prevalence of AD, advances in diagnostic capabilities and heightened awareness of the disease are projected to expand the need for AD treatments (1). Amyloid β peptide has become an important therapeutic target in AD and tau-based therapies have raised interest. Companies such as Araclon Biotech, Axon Neuroscience and AC Immune have focused on this area and amyloid β peptide vaccines and tau peptide containing candidates have reached clinical development.

Araclon Biotech is developing ABvac40, an immunotherapy for AD that uses the C-terminal fragment of the amyloid β 40 peptide as an immunogen. In 2018, the company announced a partnership with TFS International to bring ABvac40 into Phase II. In addition, Araclon Biotech is developing amyloid β peptide (1-42), ABvac42, as a therapeutic vaccine for Alzheimer’s disease. ABvac42 is in Phase I stage of development (2).

Axon Neuroscience is developing AADvac1, a vaccine containing a peptide fragment, amino acids 294 to 305 of the tau sequence, coupled to KLH. Axon Neuroscience’s vaccine is designed to stimulate patients’ immune systems to attack dysfunctional tau proteins and thereby stop the progression of AD. In 2020, the company reported positive results of the Phase II trial of AADvac1 indicating that the vaccine prevents further neuronal damage in patients and maintains levels similar to those more typically observed in healthy elderly individuals (2).

ACI-24 is a liposome-based vaccine under development by AC Immune. The vaccine contains Aβ peptide (1-15) and is designed to produce beta-sheet conformation-specific antibodies that prevent plaque deposition or enhance clearance. In 2018, the company initiated a Phase II study of ACI-24 in patients with mild AD. AC Immune is also developing ACI-35, a Phase II candidate targeting tau. ACI-35 is a liposomal vaccine containing a phosphorylated human tau protein fragment. In 2015, AC Immune partnered with Janssen Pharmaceuticals to develop ACI-35 and the vaccine is currently in a Phase Ib/IIa clinical study in patients with mild to moderate AD (2).

Diabetes

There are currently 30 synthetic peptide drug candidates in Phase I to pre-registration for diabetes. The most advanced candidate is ITCA-620, a Glucagon-Like Peptide-1 (GLP-1) receptor agonist, which is under development by Intarcia Therapeutics for the treatment of type 2 diabetes. Eli Lilly and Co is developing tirzepatide, a dual GLP-1 and Gastric Inhibitory Peptide (GIP) receptor agonist, which is in Phase III of development for the treatment of type 2 diabetes and obesity. Tirzepatide is also in Phase II stage of development for non-alcoholic steatohepatitis (NASH). Additional peptide candidates are in Phases I and II for the treatment of diabetes as shown in Figure 1.