Topic: Conjugation

20 April 2026

GLP-1 Demand: What it means for peptide manufacturers

GLP-1 receptor agonists are transforming peptide manufacturing. For decades, peptide APIs were typically produced at kilogram scale for…

30 March 2026

Linear vs Fragment SPPS for Peptide Manufacturing

As demand for complex peptide APIs reaches unprecedented scales, manufacturers face a critical strategic question: is linear solid-phase…

09 January 2026

Publications

Review the scientific articles where the Bachem team has contributed to peptide and oligonucleotide research. Arginine side-chain protection:…

05 September 2025

5 Conjugate Reactions Improving Oligonucleotide Delivery

Oligonucleotides (oligos) are short strands of DNA or RNA that look set to revolutionize the treatment of a range…

01 September 2025

Conjugation Chemistry: Improving Oligonucleotide Targeted Delivery

Oligonucleotides are emerging as a powerful new class of therapeutics that show promise as groundbreaking therapies for previously…

23 January 2025

Introduction to Cell-Permeable Peptides

PROTEIN TRANSDUCTION DOMAINS (PTDs) Cell-penetrating peptides (CPPs) constitute a promising tool for the cellular import of drug cargos.…

09 February 2022

The Thiol-Maleimide Reaction: A Guide

Secrets of an important byproduct revealed At Bachem, technological leadership and strong innovation have been the cornerstones of our success…