Topic: Innovation

03 August 2026

Case study: Verification of SAX method selectivity using 2D-LC-MS for peak purity assessment of oligonucleotide APIs

Accurate analytical characterization is essential throughout oligonucleotide development, supporting impurity profiling, stability assessment, and ultimately the delivery of…

15 July 2026

What is Tag-Assisted Peptide Synthesis (TAPS)?

As the leading peptide manufacturer, Bachem is at the forefront of innovative synthesis methods. One cutting-edge approach is…

11 June 2026

A mild and sustainable platform for disulfide bond formation in peptide manufacturing using dehydroascorbic acid

    Disulfide bond formation is a key step in the manufacture of cysteine‑containing peptides, yet established oxidation…

11 June 2026

Stirring Things Up: Integrating Stirred-Bed SPOS and Enzymatic Ligation for Industrial Oligonucleotide Production

  The rising demands for therapeutic oligonucleotides requires scalable, efficient, and more sustainable manufacturing solutions. Stirred bed technology…

03 March 2026

Tag-Assisted Peptide Synthesis (TAPS) for sustainable Peptide production

As the demand for peptide-based therapeutics continues to grow, the need for innovative, cost-efficient, and environmentally friendly manufacturing…

05 November 2025

Webinar Efficient Large-scale SiRNA Manufacturing: Enzymatic Ligation of Short RNA Fragments

  Linear synthesis by continuous-flow SPOS is the current state-of-the-art technology to manufacture oligonucleotide APIs. A very promising alternative,…

29 September 2025

Enzymatic ligation and other innovative technologies: Shaping the future of large-scale Oligonucleotide manufacturing

Oligonucleotide-based therapeutics are transforming modern medicine, offering targeted solutions for genetic disorders, cancer, cardiovascular disease, and CNS conditions.…

20 May 2025

Efficient Large-scale siRNA Manufacturing: Enzymatic Ligation of Short RNA Fragments

  Linear synthesis by continuous-flow SPOS is the current state-of-the-art technology to manufacture oligonucleotide APIs. A very promising…

17 February 2025

Innovative Approaches for Large-Scale Peptide Production

Peptides have the potential to expand the space of “druggable” targets. No wonder the number of them being under…