Biologics UK: In-Person
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Biologics UK: In-Person
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Novel approaches in MS characterization of highly modified synthetic RNA
by Giovanni Calderisi, Project Chemist QC
- Challenges in the structural characterization approaches of oligonucleotide based pharmaceuticals
- Techniques for full nucleotide sequence characterization of highly modified single-stranded and duplex RNAs
- Case Study: N-acetylgalactosamine modified RNA sense strand
- LC-MS(/MS) workflow for the characterization of product-related impurities in oligonucleotides
Impact in the process development of oligonucleotide therapeutics
DAY ONE: Monday, March 21, 11:40am