Bachem’s custom peptide synthesis services offer high-quality, reliable, flexible and cost-effective solutions for cutting-edge research in life science, drug discovery, and in vitro diagnostics development programs and commercial supply.
We are experts in producing a variety of peptides – from simple to long and challenging sequences per our customers’ specifications. Fluorescent labels, multiple disulfides, stable isotopes, and many others peptide modifications are our specialties.
What Bachem offers
We have the capability to synthesize peptides at different purity levels (crude to ≥ 97%), and scales (mg to kg) with customized solutions to meet any aliquoting requirements. Express delivery service is also available for urgent projects. Reach out today to challenge us with your ideas and take advantage of our expertise.
Large Selection of Modifications (N-, C-terminal and backbone)
- Acetylation, formylation, acylation
- Amidation
- Biotinylation
- Branched peptides
- Chromogenic and fluorogenic carboxypeptidase substrates
- Clickable peptides
- Conjugation to polymers
- Conjugation to proteins: BSA, KLH, OVA
- Conjugation to small molecules (including imaging agents)
- Cyclizations, head to tail and side chain (lactam bridge, thioether)
- Dye labeled peptides
- Hydrocarbon-stapled peptides
- Incorporation of chelating moieties such as DOTA, DPTA
- Incorporation of fluorophores or chromophores
- Incorporation of D-enantiomers and unusual amino acids
- Introduction of C-terminal alcohol and aldehyde moieties
- Introduction of C-terminal ester and thioester groups
- Labeling with stable isotopes
- Labeling with Tide FluorTM and Tide QuencherTM
- Ligations
- Lipidation
- Maleimido peptides
- Methylation, alkylation
- Multiple disulfide bond formation
- Phosphorylation and sulfation
- Retro-inverso peptides
- Stabilizing modifications including PEGylation, N-methylated amino acids and reduced peptide bonds
Higher levels of purity will require additional production efforts and time. Our recommendations are:
| Purity | Applications |
|---|---|
| >95% | NMR studies |
| Crystallography studies | |
| Peptides used as reference in final quantitative studies | |
| Enzyme-substrate studies | |
| Receptor-ligand interaction studies | |
| Blocking and competition assays | |
| 90-95% | Production of monoclonal antibodies |
| Enzyme-substrate studies (quantitative) | |
| Receptor-ligand interaction studies (quantitative) | |
| Blocking and competition assays | |
| ELISA and RIA (quantitative) | |
| In vivo/in vitro studies | |
| >80% | Western blotting studies (non-quantitative) |
| Immunograde | Production of polyclonal antibodies |
| >65% | Determination of the titer of antibodies in standard ELISA |
Why choose Bachem?
- Customer centricity & service – At Bachem, we strive to give our customers an all-round positive experience – no matter who they are or where they are located.
- Innovation and technology – We are passionate about innovation with a strong focus on realizing value in all areas of the company.
- Operational excellence and quality – Bachem is a leading and successful global player in the business of developing and manufacturing peptides and oligonucleotides.
- People & culture – Our employees make the difference. We are enthusiastic about technology and constant innovation and at the same time proud of our reliability and our solution oriented, hands-on mentality.
- Sustainability – We are committed to sustainability by taking responsibility towards our employees, the society, and the environment.
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QUOTE REQUEST FOR PEPTIDES AND AMINO ACID DERIVATIVES
Bachem offers comprehensive custom synthesis services to life scientists and researchers worldwide including the synthesis of custom peptides and organic compounds.
Complete the form below to receive a price and delivery time for your custom project.