Manufacturing pharmaceutical APIs poses several challenges for drug producers during clinical trials. These lie not just in the chemical synthesis but in scaling up the production while maintaining the quality and purity. The end goal of providing safe and effective...
Peptides and oligonucleotides (TIDES) are complex molecules whose role in medicine is growing rapidly. Demand for TIDES specialists is expected to increase as the production requires specific knowledge and technology. The global peptide market is forecast to double by...
Pharmaceutical companies contend with numerous challenges, including the imperative to invest in equipment, technology and expertise. They must meet the requirements of expansive global supply chains while concurrently reducing costs without jeopardising product...
While they were visiting Bachem, we had the chance to sit down and talk with Prof. Massimo Morbidelli, Dr. Lars Aumann, and Dr. Thomas Müller-Späth who together, have brought Continuous Chromatography from an academic idea to a potential new industry standard that...
Bachem is rapidly expanding in both capacity and capabilities across our global network to address the worldwide market needs for oligonucleotides and peptides (TIDES). Purification can be a bottleneck in TIDES production because of the enormous amounts of solvents...
Today’s technologies for producing oligonucleotides come with a high burden in terms of process mass intensity (PMI)1PMI is a measure of the quantity of raw material to produce one kilogram of isolated API.. As published in a recent paper, the PMI for producing one...
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