REDUCING SOLVENT CONSUMPTION WITH PEPTIDE EASY CLEAN

Developing and producing peptide-based drugs requires toxic reagents and enormous amounts of organic solvents. Catch-and-release methods, like Belyntic’s Peptide Easy Clean (PEC) technology, can significantly improve the ecological footprint of the entire operation. From high-throughput to large-scale projects, PEC combines green solid-phase peptide synthesis (SPPS) with a precipitation-free workup and a low solvent-consuming purification method to enable an environmentally superior solution. This webinar highlights the current advancements in this field, showcasing industry examples like green Bivalirudin manufacturing.

 

About the Speakers

Robert Zitterbart, Ph.D.

Co-Founder, Head of R&D at Belyntic GmbH

Co-Founder, Head of R&D at Belyntic GmbH, The Peptide Easy Clean (PEC) Technology

Robert Zitterbart is Co-Founder and Head of R&D at Belyntic GmbH, Berlin. There he is focusing on developing linker systems to purify and modify peptides. He has almost a decade of experience in the development of peptide purification technologies. After his diploma at the University of California, Berkeley, he earned his Ph.D. at Humboldt-University, Berlin. During his scientific career, Robert has successfully published many articles in peer reviewed journals.

Dominik Sarma, Ph.D.

Co-Founder, Managing Director at Belyntic GmbH

Co-Founder, Managing Director at Belyntic GmbH, The Peptide Easy Clean (PEC) Technology

Dominik Sarma earned his Ph.D. in advanced analytical materials at the Humboldt-University Berlin. Along with Robert Zitterbart, Oliver Reimann, and Andreas Regnery, he founded Belyntic in 2018. Together, they developed the first universally applicable, cleavable linker for catch-and-release peptide purification and modification. Dominik is the director of marketing and quality at Belyntic.

Gavin Noble

Process Optimisation Chemist

Gavin T. Noble is process optimisation chemist at Bachem UK St Helens and had the leading role at Bachem in the investigation of the Peptide Easy Clean platform. Prior to Bachem, he worked as a post-doctoral fellow at The University of Notre Dame (USA), researching peptide-targeted liposome nanoparticles for cancer and antimalarial therapies. He obtained his Ph.D. from the University of Manchester (UK). He has published several peer-reviewed articles in high impact journals during both his academic studies and career at Bachem.

Prior to his position at Bachem, he worked as a post-doctoral fellow at The University of Notre Dame (USA), researching peptide-targeted liposome nanoparticles for cancer and antimalarial therapies. He obtained his Ph.D. from The University of Manchester (UK), performing research into protein and enzyme activity at synthetic liposome surfaces. He has published several peer-reviewed articles in high impact journals during both his academic studies and career at Bachem.

Webinars