Large-scale TIDES purification with MCSGP under GMP
Throughout industry the trend goes from producing batches to continuous production. Due to the increasing need for efficient methods to produce peptides and oligonucleotides on a large scale, Bachem was the first TIDES manufacturer to introduce Multicolumn...
Tag-assisted One-Pot Liquid-phase Oligonucleotide Synthesis
Learn more on Bachem’s new one-pot process of synthesizing oligonucleotides in liquid-phase utilizing new pseudo-solid-phase protecting groups (tags). This process holds promise to be more efficient and environmentally friendly than current commercial processes....
Learn about methods for making long and complex peptides
Which of the current available production techniques should be chosen for long, complex and functionalized peptides or even small proteins? Which technologies allow functionalization of peptides? Get answers to these questions by joining our next webinar where experts...
Process-scale MCSGP purification of large synthetic molecules
In 2021, Bachem acquired the first two process-scale Multicolumn Counter-current Solvent Gradient Purification (MCSGP) systems for the purification of peptides and oligonucleotides. The systems are qualified for GMP use for which first purifications at scale were...