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Efficient Large-scale SiRNA Manufacturing: Enzymatic Ligation of Short RNA Fragments

Efficient Large-scale SiRNA Manufacturing: Enzymatic Ligation of Short RNA Fragments

Nov 5, 2025 | Generic API, Innovation, Oligos NCE, Services & Capabilities, Sustainability

Linear synthesis by continuous-flow SPOS is the current state-of-the-art technology to manufacture oligonucleotide APIs. A very promising alternative, especially to manufacture large quantities, is the enzymatic ligation of short oligonucleotide fragments. This...
Expert Round – Outsourcing in Pharma 2025

Expert Round – Outsourcing in Pharma 2025

Jul 18, 2025 | Generic API, Services & Capabilities

The expert panel discussion focused on evolving trends in the pharmaceutical industry, particularly the growing importance of external manufacturing partnerships and supply chain strategies. Representatives from Bachem’s Supply Chain, Global Exclusive APIs, and...
Expert Round – Upscaling TIDES Manufacturing 2024

Expert Round – Upscaling TIDES Manufacturing 2024

Nov 13, 2024 | Generic API, Peptides NCE, Services & Capabilities

In this engaging fireside chat, experts from Bachem discuss the rapid growth and increasing demand in the peptides market, particularly driven by GLP-1 analogs for treating diabetes, obesity, and other metabolic diseases. The conversation highlights the challenges of...
Mitigating supply chain risks in an age of disruption

Mitigating supply chain risks in an age of disruption

May 22, 2024 | Generic API, Services & Capabilities

Reliable supply of active pharmaceutical ingredients (API) is essential for the well-being of patients and global health. From sourcing responsibly to forecasting demand, anticipating bottlenecks and mitigating known and unknown risk factors, join this webinar to...
The Regulatory Perspective: Analytical Expectations for Peptide Therapeutics

The Regulatory Perspective: Analytical Expectations for Peptide Therapeutics

May 14, 2024 | Peptides NCE, Services & Capabilities

Regulatory authorities anticipate greater emphasis on analytical characterization at earlier stages of peptide therapeutics development. Let’s delve into recent insights from regulatory authorities in the United States and European Union concerning peptide...
Analytical Procedure Development for Novel Peptides: From Column Screening to GMP Releases

Analytical Procedure Development for Novel Peptides: From Column Screening to GMP Releases

May 14, 2024 | Peptides NCE, Services & Capabilities

In the current pharmaceutical landscape, therapeutic peptides are on the rise. To ensure the large-scale production of peptides in the highest quality, Bachem implements a holistic analytical control strategy. Beginning with product-specific understanding of e.g....
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