Webinar Replay about the Event Ensuring responsible sourcing of our goods and services is paramount for continuous improvement of our performance as outlined in our Corporate Social Responsibility framework. Learn more about our initiatives directed at making our supply chain more sustainable and resilient. We will talk about our supplier sustainability assessments and responsible sourcing […]
Webinar Replay about the Event In 2021, Bachem acquired the first two process-scale Multicolumn Counter-current Solvent Gradient Purification (MCSGP) systems for the purification of peptides and oligonucleotides. The systems are […]
Webinar Replay about the Event At Bachem, we are constantly striving to improve our industry standards by developing innovative and efficient large-scale manufacturing processes for active pharmaceutical ingredients (APIs). Thereby, our operations entered the Industry 4.0 era and started their business transformation towards a smart factory. Watching this webinar, you will learn more about our […]
about the Event In this webinar we will present direct, robust and easy-to-use techniques to fully characterize the nucleotide sequence of highly modified single-stranded RNAs by top down tandem MS. This will include a case study for a N-acetylgalactosamine modified RNA sense strand. The approach can be applied on a single strand level, as well […]
Which of the current available production techniques should be chosen for long, complex and functionalized peptides or even small proteins? Which technologies allow functionalization of peptides? Get answers to these questions by joining our next webinar where experts are discussing the pros and cons of today’s technologies for SPPS, native chemical ligation, CEPS, KAHA and […]
Based on decades of experience in applying stirred-bed reactors for making peptides, we investigated whether these could be used for the manufacturing of oligonucleotides as well. Join our webinar on scalable oligonucleotide manufacturing with stirred-bed technology (SBT) to learn how we can reach commercial oligonucleotides API production in metric ton range with unbeaten process mass […]
Aggregation is a complex and heterogenous process for peptides. The individual trigger for peptide aggregation is peptide specific and can be induced by standard manufacturing conditions. Therefore, it is important to evaluate and manage the manufacturing process to produce physically stable drug substances. Our experts share their analytical expertise on peptide aggregation and how to avoid it […]
Which of the current available production techniques should be chosen for long, complex and functionalized peptides or even small proteins? Which technologies allow functionalization of peptides? Get answers to these questions by joining our next webinar where experts are discussing the pros and cons of today’s technologies for SPPS, native chemical ligation, CEPS, KAHA and […]
Learn more on Bachem’s new one-pot process of synthesizing oligonucleotides in liquid-phase utilizing new pseudo-solid-phase protecting groups (tags). This process holds promise to be more efficient and environmentally friendly than current commercial processes. Distribution between a halogen-free organic and an aqueous phase allows to remove byproducts and excess reagents. No isolation of the growing oligonucleotide […]
Throughout industry the trend goes from producing batches to continuous production. Due to the increasing need for efficient methods to produce peptides and oligonucleotides on a large scale, Bachem was […]
We asked ourselves how will we need to transform and further develop PM capabilities and services to best support BACHEM‘s growth aspirations?
Cysteine (Cys) is a key amino acid in many therapeutic peptides. Cys amino acid residues, involved in the formation of two important peptide bonds, the amide and disulfide bonds, and […]
