DMF

(Des-Gly10,D-Ser(tBu)6,Pro-NHEt9)-LHRH

Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHEt
acetate salt

Use in reproduction medicine
Advanced hormone-dependent prostate cancer
Endometriosis
Central precocious puberty
Uterine myoma

Buserelin is a potent LHRH (GnRH) agonist. After a transient increase, continuous administration of buserelin results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.

Molecular Formula

C₆₀H₈₆N₁₆O₁₃

Relative Molecular Mass

1239.44 g/mol

CAS-Number

57982-77-1 (net), 68630-75-1 (acetate)

Long-term Storage

-20 ± 5 °C

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