Triptorelin Pamoate

4073237

Bachem Regulatory Documentation

DMF

Synonyms

(D-Trp6)-LHRH; Triptorelin Embonate

Sequence

Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 pamoate salt

Fields of Application

Advanced hormone-dependent prostate cancer

Active Substance

Triptorelin Pamoate (also called Triptorelin Embonate) is a potent LHRH (GnRH) agonist. Triptorelin Pamoate is a salt form of triptorelin suitable for obtaining controlled release formulations. After a transient increase, continuous administration of triptorelin results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.

Molecular Information

Molecular Formula

C64H82N18O13

Relative Molecular Mass

1311.47 g/mol

CAS-Number

57773-63-4 (net), 124508-66-3 (pamoate)

Long-term Storage

-20 ± 5°C